ID C6LPQ8_GIAIB Unreviewed; 583 AA.
AC C6LPQ8;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN ORFNames=GL50581_726 {ECO:0000313|EMBL:EET02018.1};
OS Giardia intestinalis (strain ATCC 50581 / GS clone H7) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=598745 {ECO:0000313|EMBL:EET02018.1, ECO:0000313|Proteomes:UP000002488};
RN [1] {ECO:0000313|EMBL:EET02018.1, ECO:0000313|Proteomes:UP000002488}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50581 / GS clone H7 {ECO:0000313|Proteomes:UP000002488};
RX PubMed=19696920; DOI=10.1371/journal.ppat.1000560;
RA Franzen O., Jerlstrom-Hultqvist J., Castro E., Sherwood E., Ankarklev J.,
RA Reiner D.S., Palm D., Andersson J.O., Andersson B., Svard S.G.;
RT "Draft genome sequencing of giardia intestinalis assemblage B isolate GS:
RT is human giardiasis caused by two different species?";
RL PLoS Pathog. 5:E1000560-E1000560(2009).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EET02018.1}.
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DR EMBL; ACGJ01000922; EET02018.1; -; Genomic_DNA.
DR AlphaFoldDB; C6LPQ8; -.
DR EnsemblProtists; EET02018; EET02018; GL50581_726.
DR VEuPathDB; GiardiaDB:GL50581_726; -.
DR OMA; WIRALIC; -.
DR OrthoDB; 5482398at2759; -.
DR Proteomes; UP000002488; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR PANTHER; PTHR24120:SF4; ANKYRIN REPEAT AND SOCS BOX PROTEIN 12; 1.
DR PANTHER; PTHR24120; GH07239P; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00248; ANK; 5.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023}.
FT DOMAIN 1..246
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REPEAT 473..505
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 583 AA; 65370 MW; 861FE4667C05F95B CRC64;
MSLENLDDSS VTLKTIYNQA KMDQSNLKDC CQYVCISFYS TETLPKKFFA SSIHPGWRTL
HSWIKALICD RELATEPIIW RIMSQLIRIL DHLHSASWQD DHESIRVVYR DWSPSLILLD
NLFCVKLLIP QKNISSESCA QDRSVATEDI LKISSFIAPE VLLDQPYTEK ADIYSLGTIL
YLLTSLSKPR LIESIDFDNK VASFTDTPIT LPPIYSENIY TFMGMTLCLD PSQRASVTEL
LAFPSVERAL ADLLGTRLED ASSNEDSGLS DVNTFESNGG FFSKTRPTID IKEFMDSITI
KHPNVHVKHA RLSPSSQYCP KRPIKLMPLG ETDPRCDSLG HTQLMQATIA NDAVVAGRFV
HLAGYRNNAG LTALMLAACL GYAELTKLLA MSEAQMRTQI CVRINQWVFQ EATALMFAAG
FGHTGCVKHL YGREARMIEA YKHRTALMTA CYFGHYSCVK ILAPHEARMR DIQGKTALMY
AAESNNIKCV QCLINKEAGM SMNRTNDLYS EWTALLFAVQ EGNYECIKTL APLEAHISGA
LSLDIITKDT SNVRNKLAPD QKSEISNLIT QYMNSTIIRG RSV
//
