ID   C6LR50_GIAIB            Unreviewed;       179 AA.
AC   C6LR50;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=Ser/Thr protein kinase {ECO:0000313|EMBL:EET01507.1};
GN   ORFNames=GL50581_1232 {ECO:0000313|EMBL:EET01507.1};
OS   Giardia intestinalis (strain ATCC 50581 / GS clone H7) (Giardia lamblia).
OC   Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX   NCBI_TaxID=598745 {ECO:0000313|EMBL:EET01507.1, ECO:0000313|Proteomes:UP000002488};
RN   [1] {ECO:0000313|EMBL:EET01507.1, ECO:0000313|Proteomes:UP000002488}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50581 / GS clone H7 {ECO:0000313|Proteomes:UP000002488};
RX   PubMed=19696920; DOI=10.1371/journal.ppat.1000560;
RA   Franzen O., Jerlstrom-Hultqvist J., Castro E., Sherwood E., Ankarklev J.,
RA   Reiner D.S., Palm D., Andersson J.O., Andersson B., Svard S.G.;
RT   "Draft genome sequencing of giardia intestinalis assemblage B isolate GS:
RT   is human giardiasis caused by two different species?";
RL   PLoS Pathog. 5:E1000560-E1000560(2009).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EET01507.1}.
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DR   EMBL; ACGJ01001707; EET01507.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6LR50; -.
DR   EnsemblProtists; EET01507; EET01507; GL50581_1232.
DR   VEuPathDB; GiardiaDB:GL50581_1232; -.
DR   OrthoDB; 3664029at2759; -.
DR   Proteomes; UP000002488; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   PANTHER; PTHR24120:SF4; ANKYRIN REPEAT AND SOCS BOX PROTEIN 12; 1.
DR   PANTHER; PTHR24120; GH07239P; 1.
DR   Pfam; PF12796; Ank_2; 2.
DR   SMART; SM00248; ANK; 4.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 2.
DR   PROSITE; PS50088; ANK_REPEAT; 2.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW   Kinase {ECO:0000313|EMBL:EET01507.1};
KW   Transferase {ECO:0000313|EMBL:EET01507.1}.
FT   REPEAT          57..82
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          88..120
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ   SEQUENCE   179 AA;  20542 MW;  A0BFC62F8A09A482 CRC64;
     MWAAHRGHTE VVRVLVEEEG GMQNSWGWTA LMYAARENRK DCVRLLLDRE GGMQDKDGWT
     AIMFAARHGH TECIRLLLEK EAGKYYCEGL TPLMMAARNS HTECVKLLME KEGGMYNDNG
     WTALMVAAYW NRLECARLLA EREKDMKTTR KWFGFPPGAT ALSIAKRMGH KRIASFLRK
//