ID C6LUB4_GIAIB Unreviewed; 459 AA.
AC C6LUB4;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=TRAF3-interacting protein 1 N-terminal domain-containing protein {ECO:0000259|Pfam:PF10243};
GN ORFNames=GL50581_2366 {ECO:0000313|EMBL:EET00387.1};
OS Giardia intestinalis (strain ATCC 50581 / GS clone H7) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=598745 {ECO:0000313|EMBL:EET00387.1, ECO:0000313|Proteomes:UP000002488};
RN [1] {ECO:0000313|EMBL:EET00387.1, ECO:0000313|Proteomes:UP000002488}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50581 / GS clone H7 {ECO:0000313|Proteomes:UP000002488};
RX PubMed=19696920; DOI=10.1371/journal.ppat.1000560;
RA Franzen O., Jerlstrom-Hultqvist J., Castro E., Sherwood E., Ankarklev J.,
RA Reiner D.S., Palm D., Andersson J.O., Andersson B., Svard S.G.;
RT "Draft genome sequencing of giardia intestinalis assemblage B isolate GS:
RT is human giardiasis caused by two different species?";
RL PLoS Pathog. 5:E1000560-E1000560(2009).
CC -!- SIMILARITY: Belongs to the TRAF3IP1 family.
CC {ECO:0000256|ARBA:ARBA00043971}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EET00387.1}.
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DR EMBL; ACGJ01002305; EET00387.1; -; Genomic_DNA.
DR AlphaFoldDB; C6LUB4; -.
DR EnsemblProtists; EET00387; EET00387; GL50581_2366.
DR VEuPathDB; GiardiaDB:GL50581_2366; -.
DR OMA; MRTELHT; -.
DR OrthoDB; 5483197at2759; -.
DR Proteomes; UP000002488; Unassembled WGS sequence.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR Gene3D; 1.10.418.50; Microtubule-binding protein MIP-T3; 1.
DR InterPro; IPR018799; TRAF3IP1.
DR InterPro; IPR040468; TRAF3IP1_N.
DR InterPro; IPR042576; TRAF3IP1_N_sf.
DR PANTHER; PTHR31363; TRAF3-INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR31363:SF0; TRAF3-INTERACTING PROTEIN 1; 1.
DR Pfam; PF10243; MIP-T3; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212}.
FT DOMAIN 9..115
FT /note="TRAF3-interacting protein 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10243"
FT REGION 149..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 342..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..193
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..208
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..236
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 350..364
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 459 AA; 51595 MW; F8CD3A692B39555B CRC64;
MTTIETELIN STIDALKELI SRPPLTEKLL SRPPFKYILD ICKAVSAVTG FPSPESCNHD
DITDREERAA FLSSVIGQIS DQLGVPVDVQ IKSILAGKDV PKTLRMLVML AQAAKLFKVG
STPLQQQQAP KEAPAAPPQE DLEALARERA EKERQQREQE QREQQERERK EQERRERERR
ELEARERAEK EKQQQQQQQQ QPVELSASPQ KSPPKVRFAD DETAKVEDHR PIIERPHFNR
PPPSQHSRRM AVTATAESTV PQPSAMRLVK VIREESSDEN DQDIVQNDNQ DGGFTIGLDS
EWCEEMLPSG LGADDGASLP SGAHGELVAN ILDTAEEYNV ALHGDSKRPT GLSNQKDKKP
MDSHSQPVQK LISHISTIIR KSVPYTKHTA FLDEHILTMR TELHTASEAV TKLLSTSLKQ
ESSLKQANNA CESKIHSLKE QIYSLRQTQL ELLHSTLVL
//
