ID C6PSS1_9CLOT Unreviewed; 444 AA.
AC C6PSS1;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Transcriptional regulator, GntR family with aminotransferase domain {ECO:0000313|EMBL:EET87750.1};
GN ORFNames=CcarbDRAFT_1838 {ECO:0000313|EMBL:EET87750.1};
OS Clostridium carboxidivorans P7.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=536227 {ECO:0000313|EMBL:EET87750.1, ECO:0000313|Proteomes:UP000004198};
RN [1] {ECO:0000313|EMBL:EET87750.1, ECO:0000313|Proteomes:UP000004198}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P7 {ECO:0000313|EMBL:EET87750.1,
RC ECO:0000313|Proteomes:UP000004198};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Larimer F., Land M.L., Hauser L., Hemme C.L.;
RT "The draft genome of Clostridium carboxidivorans P7.";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EET87750.1}.
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DR EMBL; ACVI01000024; EET87750.1; -; Genomic_DNA.
DR RefSeq; WP_007060723.1; NZ_CP011803.1.
DR AlphaFoldDB; C6PSS1; -.
DR KEGG; cck:Ccar_12440; -.
DR PATRIC; fig|536227.13.peg.2606; -.
DR eggNOG; COG1167; Bacteria.
DR OrthoDB; 163333at2; -.
DR Proteomes; UP000004198; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:EET87750.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000004198};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:EET87750.1}.
FT DOMAIN 2..70
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 444 AA; 51282 MW; 785EDB86B604F243 CRC64;
MDNKYSKIAD YIKEEIHSGN LKPGNKVPSI IDICKSFKCS KSTAIRAYEE LQKQHLLYSI
SKSGFYVVEN DLVKQESHDF LIDFYSASPD ASLLPYEEFQ HSINQAIRIY KDSLFSYSNV
QGNLELRKTF KNHLRDLHIF TKVENVMVTS GSQQAIYVLS KIPFPNGKGK VLIEQPTYYG
MIKSLEYNEV ATVGIKRDIN GFDIDELEEI FKNEDIKFFY IQPRFQNPTG FSLSNNQKKG
ILKLAKKYDV YIIEDDYLAD LETNSKNETM YSIDTSDRVV YIKSFSKTLL PGLRVALLIL
PQSLVNIFLH HKACCDFITN PLSQGALDIY LKSGMYDNHL KNIKKFYSKQ MKILKDAVNL
EFSSPSHVFV PSTGFFASIE VPNLLEVMDI ENMLKSQKVR ILNVHNMFLD EYKKNNIFRL
SICRVNKQQI YEGIKIITKE LNKK
//
