ID C6PTT2_9CLOT Unreviewed; 468 AA.
AC C6PTT2;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Transcriptional regulator, GntR family {ECO:0000313|EMBL:EET87322.1};
GN ORFNames=CcarbDRAFT_2199 {ECO:0000313|EMBL:EET87322.1};
OS Clostridium carboxidivorans P7.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=536227 {ECO:0000313|EMBL:EET87322.1, ECO:0000313|Proteomes:UP000004198};
RN [1] {ECO:0000313|EMBL:EET87322.1, ECO:0000313|Proteomes:UP000004198}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P7 {ECO:0000313|EMBL:EET87322.1,
RC ECO:0000313|Proteomes:UP000004198};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Larimer F., Land M.L., Hauser L., Hemme C.L.;
RT "The draft genome of Clostridium carboxidivorans P7.";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EET87322.1}.
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DR EMBL; ACVI01000032; EET87322.1; -; Genomic_DNA.
DR RefSeq; WP_007061084.1; NZ_GG770694.1.
DR AlphaFoldDB; C6PTT2; -.
DR KEGG; cck:Ccar_11480; -.
DR PATRIC; fig|536227.13.peg.2402; -.
DR eggNOG; COG1167; Bacteria.
DR OrthoDB; 9808770at2; -.
DR Proteomes; UP000004198; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000004198};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 14..82
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 468 AA; 54160 MW; F2744A9C10362B62 CRC64;
MVEIMPIWDY SKNTPLYVQL YEYIKHEIQI GTIKPETKLP SKRKLSTYLG ISQNTIQTAY
EQLCAEGYVE SRPRIGMFVT KIEDNLSCNT PLSNKPDKSI KLNEEFKYLI DFSSGNVDLE
HFPYCTWRKL TTQCLYSDQS NLLLIGESQG EECLRKEISK YLFQSRSVRC IPEQIIIGAG
MQYLMILLCM LLGKDYTYAI ENPGFNKARN VFIDQGLDVH PISIDEDGIC VEDLRKSSAK
VVYVTPSHQF PCGMVMPVSR RLELLKWCEE KNGYIIEDDY DSEFRYRGKP IPSLQGLDRN
GKVIYMGTFS KSLIPSIRIS YLVLPQNLIE KYQKYLKIYK QTVSRLHQNT LYKFMKEGYF
SSHINKMRTL YRKKHSILLS SIDKHMKEKT EVIGANSGLH ILLKVKNGMT EEELIQCAHD
VKIKIYPTSI HYNQCLSSEF PMILLGFGGL TEKQIEDGIK ILKKAWLI
//
