ID C6SBL5_NEIME Unreviewed; 283 AA.
AC C6SBL5;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=RNA polymerase sigma-54 factor {ECO:0000313|EMBL:CBA05079.1};
GN Name=rpoN {ECO:0000313|EMBL:CBA05079.1};
GN ORFNames=NME_0677 {ECO:0000313|EMBL:CBA05079.1};
OS Neisseria meningitidis alpha153.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=663926 {ECO:0000313|EMBL:CBA05079.1};
RN [1] {ECO:0000313|EMBL:CBA05079.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Alpha153 {ECO:0000313|EMBL:CBA05079.1};
RX PubMed=18305155; DOI=10.1073/pnas.0800151105;
RA Schoen C., Blom J., Claus H., Schramm-Glueck A., Brandt P., Mueller T.,
RA Goesmann A., Joseph B., Konietzny S., Kurzai O., Schmitt C., Friedrich T.,
RA Linke B., Vogel U., Frosch M.;
RT "Whole-genome comparison of disease and carriage strains provides insights
RT into virulence evolution in Neisseria meningitidis.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:3473-3478(2008).
CC -!- SIMILARITY: Belongs to the sigma-54 factor family.
CC {ECO:0000256|ARBA:ARBA00008798}.
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DR EMBL; AM889137; CBA05079.1; -; Genomic_DNA.
DR AlphaFoldDB; C6SBL5; -.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001216; F:DNA-binding transcription activator activity; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.10.1330; RNA polymerase sigma-54 factor, core-binding domain; 1.
DR InterPro; IPR000394; RNA_pol_sigma_54.
DR InterPro; IPR007046; RNA_pol_sigma_54_core-bd.
DR InterPro; IPR007634; RNA_pol_sigma_54_DNA-bd.
DR InterPro; IPR038709; RpoN_core-bd_sf.
DR PANTHER; PTHR32248; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR PANTHER; PTHR32248:SF4; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR Pfam; PF00309; Sigma54_AID; 1.
DR Pfam; PF04963; Sigma54_CBD; 1.
DR Pfam; PF04552; Sigma54_DBD; 1.
DR PROSITE; PS00718; SIGMA54_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 80..240
FT /note="RNA polymerase sigma factor 54 core-binding"
FT /evidence="ECO:0000259|Pfam:PF04963"
FT DOMAIN 241..280
FT /note="RNA polymerase sigma factor 54 DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF04552"
SQ SEQUENCE 283 AA; 31492 MW; C5E0499177BB76C5 CRC64;
MTLLGIKLKQ TQQLNQRLQQ SLRVLQMSGI ELEREVENWL SDNPLLERKD TDEFSDAEFS
HYTAPARQIG GDEGEDMLSN IAGEQDFKQY LHAQVCEHPL SDQESACVHI LIDFLDEQGY
LTDSIEDILD HTPLEWMLDE AMLKQALTAL KKFDPAGVAA ADLNESLILQ IERSGECAAK
PSALHIVRNA LDSIDGNRSQ TLARIKKRLP QTDSGTLEAA LDLIASLNPF PAAGFASSTP
TPYSDEALAN LLAFRGMEVS RRTIAKYRES FEIPAAHKRK TAE
//
