ID C6SIF3_NEIME Unreviewed; 335 AA.
AC C6SIF3;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=IS1106 transposase {ECO:0000313|EMBL:CBA06019.1};
GN ORFNames=NMW_0723 {ECO:0000313|EMBL:CBA06019.1}, NMW_1629
GN {ECO:0000313|EMBL:CBA08737.1};
OS Neisseria meningitidis alpha275.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=295996 {ECO:0000313|EMBL:CBA06019.1};
RN [1] {ECO:0000313|EMBL:CBA06019.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Alpha275 {ECO:0000313|EMBL:CBA06019.1};
RX PubMed=18305155; DOI=10.1073/pnas.0800151105;
RA Schoen C., Blom J., Claus H., Schramm-Glueck A., Brandt P., Mueller T.,
RA Goesmann A., Joseph B., Konietzny S., Kurzai O., Schmitt C., Friedrich T.,
RA Linke B., Vogel U., Frosch M.;
RT "Whole-genome comparison of disease and carriage strains provides insights
RT into virulence evolution in Neisseria meningitidis.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:3473-3478(2008).
CC -!- FUNCTION: Involved in the transposition of the insertion sequence IS5.
CC {ECO:0000256|ARBA:ARBA00003544}.
CC -!- SIMILARITY: Belongs to the transposase 11 family.
CC {ECO:0000256|ARBA:ARBA00010075}.
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DR EMBL; AM889138; CBA06019.1; -; Genomic_DNA.
DR EMBL; AM889138; CBA08737.1; -; Genomic_DNA.
DR AlphaFoldDB; C6SIF3; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR GO; GO:0006313; P:DNA transposition; IEA:InterPro.
DR InterPro; IPR047959; Transpos_IS5.
DR InterPro; IPR002559; Transposase_11.
DR InterPro; IPR008490; Transposase_InsH_N.
DR NCBIfam; NF033581; transpos_IS5_4; 1.
DR PANTHER; PTHR35604; TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED; 1.
DR PANTHER; PTHR35604:SF2; TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED; 1.
DR Pfam; PF01609; DDE_Tnp_1; 1.
DR Pfam; PF05598; DUF772; 1.
PE 3: Inferred from homology;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464};
KW Transposition {ECO:0000256|ARBA:ARBA00022578}.
FT DOMAIN 51..122
FT /note="Transposase InsH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05598"
FT DOMAIN 139..322
FT /note="Transposase IS4-like"
FT /evidence="ECO:0000259|Pfam:PF01609"
SQ SEQUENCE 335 AA; 38505 MW; D2AE0F3D5F6DC8DF CRC64;
MSTFFQQTAQ AMIARHIDRF PLLKLDQVID WQPIEQYLNR QKTRYLRDHR GRPACPLLSM
FKAVLLGQWH SLSDPELEHS LITRIDFNLF CRFDELIIPD YSTLCRYRNW LAQDDTLSEL
LKLINCQLTE KGLKIEKASA AVVDATIIQT AGSKQRQAIE VDEEGQISGQ TTPSKDSDAR
WIKKNGLYKL GYKQHTRTDA EGYIEKLHIT PANAHECKHL SPLLEGLPKG TTVYADKGYD
SAENRQHLEE HQLQDGIMRK ACRNRPLTET QTKRNRYLSK TRYVVEQSFG TLHRKFRYAR
STYFGLIKVS AQSHLKAMCL NLLKAANRLS APAAA
//
