ID C6SKE0_NEIME Unreviewed; 335 AA.
AC C6SKE0;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=IS1106 transposase {ECO:0000313|EMBL:CBA08095.1};
GN ORFNames=NMW_1410 {ECO:0000313|EMBL:CBA08095.1};
OS Neisseria meningitidis alpha275.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=295996 {ECO:0000313|EMBL:CBA08095.1};
RN [1] {ECO:0000313|EMBL:CBA08095.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Alpha275 {ECO:0000313|EMBL:CBA08095.1};
RX PubMed=18305155; DOI=10.1073/pnas.0800151105;
RA Schoen C., Blom J., Claus H., Schramm-Glueck A., Brandt P., Mueller T.,
RA Goesmann A., Joseph B., Konietzny S., Kurzai O., Schmitt C., Friedrich T.,
RA Linke B., Vogel U., Frosch M.;
RT "Whole-genome comparison of disease and carriage strains provides insights
RT into virulence evolution in Neisseria meningitidis.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:3473-3478(2008).
CC -!- FUNCTION: Involved in the transposition of the insertion sequence IS5.
CC {ECO:0000256|ARBA:ARBA00003544}.
CC -!- SIMILARITY: Belongs to the transposase 11 family.
CC {ECO:0000256|ARBA:ARBA00010075}.
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DR EMBL; AM889138; CBA08095.1; -; Genomic_DNA.
DR AlphaFoldDB; C6SKE0; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR GO; GO:0006313; P:DNA transposition; IEA:InterPro.
DR InterPro; IPR047959; Transpos_IS5.
DR InterPro; IPR002559; Transposase_11.
DR InterPro; IPR008490; Transposase_InsH_N.
DR NCBIfam; NF033581; transpos_IS5_4; 1.
DR PANTHER; PTHR35604; TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED; 1.
DR PANTHER; PTHR35604:SF2; TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED; 1.
DR Pfam; PF01609; DDE_Tnp_1; 1.
DR Pfam; PF05598; DUF772; 1.
PE 3: Inferred from homology;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464};
KW Transposition {ECO:0000256|ARBA:ARBA00022578}.
FT DOMAIN 51..122
FT /note="Transposase InsH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05598"
FT DOMAIN 139..322
FT /note="Transposase IS4-like"
FT /evidence="ECO:0000259|Pfam:PF01609"
SQ SEQUENCE 335 AA; 38568 MW; 5640E9C3A077FD42 CRC64;
MSTFFRQTAQ AMIAKHIDRF PLLKLDQVID WQPIEQYLNR QKTRYLRDHR GRPAYPLLSM
FKAILPGQWH SLSDPELEHS LITRIDFNLF CRFDELSIPD YSTLCRYRNW LAQDDTLSEL
LELINRQLTE KGLKIEKASA AAVDATIIQT AGSKQRQAIE VDEEGQVSGQ TTPSKDSDAR
WIKKNGLYKL GYKQHTRTDG EGYIEKLHIT PTNAHECTHL SPLLEGLPKG TTVYADKGYD
SKENRQHLKE HRLQNGIMRK ACRNRPLTET QTKHNRYLSK IRYVVEQSFG TLHRKFRYAR
AAYFGLIKVS AQSHLKAMCL NLLKAANRLS APAAA
//
