ID   C6TPA7_DROME            Unreviewed;       581 AA.
AC   C6TPA7;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   03-APR-2013, entry version 25.
DE   SubName: Full=AT12251p;
GN   Name=Top1-RB;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RA   Carlson J., Booth B., Frise E., Park S., Wan K., Yu C., Celniker S.;
RL   Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; BT099593; ACU45746.1; -; mRNA.
DR   Bgee; C6TPA7; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0003917; F:DNA topoisomerase type I activity; IEA:InterPro.
DR   GO; GO:0003918; F:DNA topoisomerase type II (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   Gene3D; 1.10.10.41; -; 1.
DR   Gene3D; 1.10.132.10; -; 1.
DR   Gene3D; 2.170.11.10; -; 2.
DR   Gene3D; 3.90.15.10; -; 1.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013034; DNA_topo_domain1.
DR   InterPro; IPR001631; TopoI.
DR   InterPro; IPR018521; TopoI_AS.
DR   InterPro; IPR025834; TopoI_C_dom.
DR   InterPro; IPR014711; TopoI_cat_a-hlx-sub_euk.
DR   InterPro; IPR014727; TopoI_cat_a/b-sub_euk.
DR   InterPro; IPR013500; TopoI_cat_euk.
DR   InterPro; IPR008336; TopoI_DNA-bd_euk.
DR   InterPro; IPR013030; TopoI_DNA-bd_mixed-a/b_euk.
DR   InterPro; IPR013499; TopoI_euk.
DR   InterPro; IPR009054; TopoI_insert_euk.
DR   Pfam; PF14370; Topo_C_assoc; 1.
DR   Pfam; PF01028; Topoisom_I; 1.
DR   Pfam; PF02919; Topoisom_I_N; 1.
DR   PRINTS; PR00416; EUTPISMRASEI.
DR   SMART; SM00435; TOPEUc; 1.
DR   SUPFAM; SSF56349; DNA_brk_join_enz; 1.
DR   SUPFAM; SSF46596; Topismrse_insert; 1.
DR   SUPFAM; SSF56741; TopoI_DNA_bd_euk; 1.
DR   PROSITE; PS00176; TOPOISOMERASE_I_EUK; 1.
PE   2: Evidence at transcript level;
SQ   SEQUENCE   581 AA;  68672 MW;  626135543A753158 CRC64;
     MLYNRKNFFC QEPEPAVSPG KRQKAKAKVE EEEVWRWWEE EKRADGVKWS TLEHKGPVFA
     PRYERVPRNV RFYYDGKPLE LSEETEEAAT FYAKMLNHDY CTKEVFNNNF FKDFRKSMTP
     REREIIKDFR KCNFQEMFNY FQAESEKRKA ASKEEKLIKK NENEALMKEF GFCMIDGHKE
     KIGNFRLEPP GLFRGRGEHP KMGMIKRRIQ ASDVSINCGK DSKVPSPPPG SRWKEVRHDN
     TVTWLASWIE NVQGQVKYIM LNPSSKLKGE KDHIKYETAR RLDKVIDKIR ATYRDEWKSK
     EMRVRQRAVA LYFIDKLALR AGNEKDEDQA DTVGCCSLRV EHVQLHKELN GKENVVVFDF
     PGKDSIRYYN EVEVEKRVFK NLELFMEHKK EGDDLFDRLK TQVLNEHLKE LMEGLTAKVF
     RTYNASKTLQ SQLDLLTDPS ATVPEKLLAY NRANRAVAIL CNHQRSVPKS HEKSMENLKE
     KIKAKREAIE KCESEYHSRD EKKGKQLERL RDQLKKLELQ ETDRDENKTI ALGTSKLNYL
     DPRISVAWCK KHDVPIEKIF NKTQRTKFLW AVHMADENYR F
//