ID C6W8L8_ACTMD Unreviewed; 204 AA.
AC C6W8L8;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Transcriptional regulator, TetR family {ECO:0000313|EMBL:ACU37117.1};
GN OrderedLocusNames=Amir_3208 {ECO:0000313|EMBL:ACU37117.1};
OS Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064
OS / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinosynnema.
OX NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU37117.1, ECO:0000313|Proteomes:UP000002213};
RN [1] {ECO:0000313|EMBL:ACU37117.1, ECO:0000313|Proteomes:UP000002213}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 /
RC NRRL B-12336 / IMRU 3971 / 101 {ECO:0000313|Proteomes:UP000002213};
RX PubMed=21304636; DOI=10.4056/sigs.21137;
RA Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D., Goodwin L.,
RA Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavromatis K.,
RA Chen A., Palaniappan K., Hauser L., Chang Y.J., Jeffries C.C., Brettin T.,
RA Detter J.C., Han C., Chain P., Tindall B.J., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL Stand. Genomic Sci. 1:46-53(2009).
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DR EMBL; CP001630; ACU37117.1; -; Genomic_DNA.
DR RefSeq; WP_015802006.1; NC_013093.1.
DR AlphaFoldDB; C6W8L8; -.
DR STRING; 446462.Amir_3208; -.
DR KEGG; ami:Amir_3208; -.
DR eggNOG; COG1309; Bacteria.
DR HOGENOM; CLU_069356_21_0_11; -.
DR OrthoDB; 7506349at2; -.
DR Proteomes; UP000002213; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR041583; TetR_C_31.
DR Pfam; PF17940; TetR_C_31; 1.
DR Pfam; PF00440; TetR_N; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000002213};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 6..66
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 29..48
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 204 AA; 22236 MW; 8EEE1AC8B8B80925 CRC64;
MARRNPERRA ALLDAAVEVL AGDGARGLTF RAVDQRAGVP AGTASNYFAG RAEILTGAGE
RVYQRLLDQA LLTETLDGPR DRARVTELTH ALVDRVSAFP TGFLALLELR LEAARSPELR
EVLTARVRAD LRFNAEHHAA SGLPGDGTTV ALLWLALNWL VLERLTLPDL LTDDQRRDLV
TALVDRLLAG QPERAVDPFG ESGR
//
