ID C6WBY0_ACTMD Unreviewed; 292 AA.
AC C6WBY0;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE SubName: Full=GCN5-related N-acetyltransferase {ECO:0000313|EMBL:ACU37547.1};
GN OrderedLocusNames=Amir_3663 {ECO:0000313|EMBL:ACU37547.1};
OS Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064
OS / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinosynnema.
OX NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU37547.1, ECO:0000313|Proteomes:UP000002213};
RN [1] {ECO:0000313|EMBL:ACU37547.1, ECO:0000313|Proteomes:UP000002213}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 /
RC NRRL B-12336 / IMRU 3971 / 101 {ECO:0000313|Proteomes:UP000002213};
RX PubMed=21304636; DOI=10.4056/sigs.21137;
RA Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D., Goodwin L.,
RA Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavromatis K.,
RA Chen A., Palaniappan K., Hauser L., Chang Y.J., Jeffries C.C., Brettin T.,
RA Detter J.C., Han C., Chain P., Tindall B.J., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL Stand. Genomic Sci. 1:46-53(2009).
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DR EMBL; CP001630; ACU37547.1; -; Genomic_DNA.
DR RefSeq; WP_015802434.1; NC_013093.1.
DR AlphaFoldDB; C6WBY0; -.
DR STRING; 446462.Amir_3663; -.
DR KEGG; ami:Amir_3663; -.
DR eggNOG; COG1670; Bacteria.
DR eggNOG; COG2764; Bacteria.
DR HOGENOM; CLU_951979_0_0_11; -.
DR OrthoDB; 3681341at2; -.
DR Proteomes; UP000002213; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.10.180.10; 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR029068; Glyas_Bleomycin-R_OHBP_Dase.
DR InterPro; IPR000182; GNAT_dom.
DR PANTHER; PTHR43792; GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED; 1.
DR PANTHER; PTHR43792:SF1; N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13302; Acetyltransf_3; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF54593; Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase; 1.
DR PROSITE; PS51186; GNAT; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002213};
KW Transferase {ECO:0000313|EMBL:ACU37547.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 71..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..168
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
SQ SEQUENCE 292 AA; 31313 MW; 5123AA4192535B7A CRC64;
MDLRTSRLEL LPLDPDEHAE ALHAVYGDPA VMRWWTCPER ASVERTRQLL TEELAGPGAL
LWAVRRAEDG AVIGVTGLLG GVALPGLTWI LARRAWGRGF AAEAAAAVVD HAFRHVGHDR
VEAWVESTNT RSIAVCRKVG LTERGRFVQR YGHRDRPHEM IVLGRAGTPD PVSVVHLQPV
VQVVDVAATA ALLVAVLGAR VSFIAGEPAH VAGIVLGPWS TGPGLRLVRP PRGECAPVEL
VLDVGPGFVG LRESALASGV AGVEPIVDQP WGRREFALRL PEGHRVVLST PS
//
