ID C6WIL1_ACTMD Unreviewed; 295 AA.
AC C6WIL1;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Transcriptional regulator, LysR family {ECO:0000313|EMBL:ACU38101.1};
GN OrderedLocusNames=Amir_4246 {ECO:0000313|EMBL:ACU38101.1};
OS Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064
OS / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinosynnema.
OX NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU38101.1, ECO:0000313|Proteomes:UP000002213};
RN [1] {ECO:0000313|EMBL:ACU38101.1, ECO:0000313|Proteomes:UP000002213}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 /
RC NRRL B-12336 / IMRU 3971 / 101 {ECO:0000313|Proteomes:UP000002213};
RX PubMed=21304636; DOI=10.4056/sigs.21137;
RA Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D., Goodwin L.,
RA Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavromatis K.,
RA Chen A., Palaniappan K., Hauser L., Chang Y.J., Jeffries C.C., Brettin T.,
RA Detter J.C., Han C., Chain P., Tindall B.J., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL Stand. Genomic Sci. 1:46-53(2009).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; CP001630; ACU38101.1; -; Genomic_DNA.
DR RefSeq; WP_015802988.1; NC_013093.1.
DR AlphaFoldDB; C6WIL1; -.
DR STRING; 446462.Amir_4246; -.
DR KEGG; ami:Amir_4246; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_0_11; -.
DR OrthoDB; 3286335at2; -.
DR Proteomes; UP000002213; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30346:SF16; SMALL NEUTRAL PROTEASE REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002213}.
FT DOMAIN 4..61
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 295 AA; 30527 MW; A1940CB3A8B1BE2D CRC64;
MSGMTLLGLR VVVEVARRGS FTAAAEVLGY TQSAVSRQVG AMETAAGGPL FERGARGVRP
TPAGEALLRH AGQVVAHVEA AELEIAGLRD RLAGRLVVGA YPTAAAALVP SAVARLRAAH
PALAVSLGEA GSPALLRRLR AGRLEVAVIA VGDGLPDYDL TGLVVEQVPG QRGMGVAVAD
DHPFARQSEV DVAQLADQVW VVGVGKEGEP QFGAWPTLAD PVVGHEARSW PTRFGLVKAG
LGITVLPGLA AGTAPRGVTW VPVRDPELVW GRRTVALTRP DRSDAAGAFV RALRG
//
