ID C6WLU7_ACTMD Unreviewed; 562 AA.
AC C6WLU7;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Glucose-methanol-choline oxidoreductase {ECO:0000313|EMBL:ACU40332.1};
GN OrderedLocusNames=Amir_6532 {ECO:0000313|EMBL:ACU40332.1};
OS Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064
OS / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinosynnema.
OX NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU40332.1, ECO:0000313|Proteomes:UP000002213};
RN [1] {ECO:0000313|EMBL:ACU40332.1, ECO:0000313|Proteomes:UP000002213}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 /
RC NRRL B-12336 / IMRU 3971 / 101 {ECO:0000313|Proteomes:UP000002213};
RX PubMed=21304636; DOI=10.4056/sigs.21137;
RA Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D., Goodwin L.,
RA Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavromatis K.,
RA Chen A., Palaniappan K., Hauser L., Chang Y.J., Jeffries C.C., Brettin T.,
RA Detter J.C., Han C., Chain P., Tindall B.J., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL Stand. Genomic Sci. 1:46-53(2009).
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DR EMBL; CP001630; ACU40332.1; -; Genomic_DNA.
DR RefSeq; WP_015805215.1; NC_013093.1.
DR AlphaFoldDB; C6WLU7; -.
DR STRING; 446462.Amir_6532; -.
DR KEGG; ami:Amir_6532; -.
DR eggNOG; COG2303; Bacteria.
DR HOGENOM; CLU_002483_2_0_11; -.
DR OrthoDB; 517968at2; -.
DR Proteomes; UP000002213; Chromosome.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 3.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR47470; CHOLESTEROL OXIDASE; 1.
DR PANTHER; PTHR47470:SF1; FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000002213}.
FT DOMAIN 11..44
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 76..278
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00732"
FT DOMAIN 463..520
FT /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05199"
SQ SEQUENCE 562 AA; 59525 MW; 01A2193A59C2956C CRC64;
MAEPGEGVDH DVVVVGSGFG GSVAALRLTE KGYRVAVVEA GRRFSDDEFA ETSWDVRRYL
WAPALGCYGI QRVHVLRDVV VLAGAGVGGG SLVYANTLYR PPSAFFLDRQ WAHITDWESE
LAPHYDQASR VLGVVANPDR TPSDVVLERV AERMGVRDTY RPTPVGVHFG RPGEVAADPY
FGGVGPSRAG CTRCGACMTG CRVGAKNTLV KNYLHLAELA GARVLPMSTA TEVRPRGDGT
WAVRIRRTGG PRSAERVLTA GQVVLAAGAW GTQRLLHRMR DDGVLPGLSP RLGELTRTNS
EAITGAGRFR VDPGRDFSAG VAITSSMHPD ADTHVEAVRF GRGSNLMGLL QTLATDGGSA
TPRFAQFLAA VARDPVRAVR LLSVRRWSER TVILLVMQSL DNSLTTFGKR GVFGRWRLGS
GQGHGAPNPS YIAAGARAGE LAAEEIGGVA GGAIGELFDV PMTAHFLGGC AIGEDWGSGV
VDPYLRVHGY PGLSVVDGAA VSANLGVNPS LTIAAQAERA FSLWPNAGEA DTRPAQGEGY
RRVRVVRPRA PVVPEGAVGA LR
//
