ID   C6WMH3_ACTMD            Unreviewed;       364 AA.
AC   C6WMH3;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   SubName: Full=Alanine racemase domain protein {ECO:0000313|EMBL:ACU36502.1};
GN   OrderedLocusNames=Amir_2565 {ECO:0000313|EMBL:ACU36502.1};
OS   Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064
OS   / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101).
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Actinosynnema.
OX   NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU36502.1, ECO:0000313|Proteomes:UP000002213};
RN   [1] {ECO:0000313|EMBL:ACU36502.1, ECO:0000313|Proteomes:UP000002213}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 /
RC   NRRL B-12336 / IMRU 3971 / 101 {ECO:0000313|Proteomes:UP000002213};
RX   PubMed=21304636; DOI=10.4056/sigs.21137;
RA   Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA   Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D., Goodwin L.,
RA   Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavromatis K.,
RA   Chen A., Palaniappan K., Hauser L., Chang Y.J., Jeffries C.C., Brettin T.,
RA   Detter J.C., Han C., Chain P., Tindall B.J., Bristow J., Eisen J.A.,
RA   Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL   Stand. Genomic Sci. 1:46-53(2009).
CC   -!- SIMILARITY: Belongs to the DSD1 family.
CC       {ECO:0000256|ARBA:ARBA00005323}.
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DR   EMBL; CP001630; ACU36502.1; -; Genomic_DNA.
DR   RefSeq; WP_015801391.1; NC_013093.1.
DR   AlphaFoldDB; C6WMH3; -.
DR   STRING; 446462.Amir_2565; -.
DR   KEGG; ami:Amir_2565; -.
DR   eggNOG; COG3616; Bacteria.
DR   HOGENOM; CLU_031639_2_2_11; -.
DR   OrthoDB; 9811417at2; -.
DR   Proteomes; UP000002213; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProt.
DR   Gene3D; 3.20.20.10; Alanine racemase; 1.
DR   Gene3D; 2.40.37.20; D-serine dehydratase-like domain; 1.
DR   InterPro; IPR001608; Ala_racemase_N.
DR   InterPro; IPR026956; D-ser_dehydrat-like_dom.
DR   InterPro; IPR042208; D-ser_dehydrat-like_sf.
DR   InterPro; IPR029066; PLP-binding_barrel.
DR   PANTHER; PTHR28004:SF2; D-SERINE DEHYDRATASE; 1.
DR   PANTHER; PTHR28004; ZGC:162816-RELATED; 1.
DR   Pfam; PF01168; Ala_racemase_N; 1.
DR   Pfam; PF14031; D-ser_dehydrat; 1.
DR   SMART; SM01119; D-ser_dehydrat; 1.
DR   SUPFAM; SSF51419; PLP-binding barrel; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002213};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        229..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          243..350
FT                   /note="D-serine dehydratase-like"
FT                   /evidence="ECO:0000259|SMART:SM01119"
SQ   SEQUENCE   364 AA;  38312 MW;  D4BB470EC44C4663 CRC64;
     MTPPTPHLRL DREVLRRNAD RLRARITALG PVLRPHVKTS KSPRVAEVLL GGAPGPITVS
     TLREAEVFAD AGYDDVLYAV GIAPSKLDRV RALRERGVDL VVLLDSVEQA EAVAGQGVPA
     LLEVDCDGHR GGVPPDSPAV LEIAGVLGGD LLRGVLTHAG ESYFRYTPEE LALAAEHERA
     TAVRVAEALR AGGFPCPVVS VGSTPTAHAA RDLTGVTEVR AGNYAFFDLV MAGVGVCGLA
     DLALSVVVTV IGHRRERGWI MTDGGWMATS RDRGTGVQAV DQAYGVVALE DGGVVPDLLM
     VGASQEHGVL GMREGSAREL PDFPVGTRLR VLPVHACATA AQHGEYHVVG GGRAPEVWAR
     VTGW
//