ID   C6WPD6_ACTMD            Unreviewed;      1067 AA.
AC   C6WPD6;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   SubName: Full=Putative signal transduction protein with Nacht domain {ECO:0000313|EMBL:ACU38638.1};
GN   OrderedLocusNames=Amir_4811 {ECO:0000313|EMBL:ACU38638.1};
OS   Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064
OS   / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101).
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Actinosynnema.
OX   NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU38638.1, ECO:0000313|Proteomes:UP000002213};
RN   [1] {ECO:0000313|EMBL:ACU38638.1, ECO:0000313|Proteomes:UP000002213}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 /
RC   NRRL B-12336 / IMRU 3971 / 101 {ECO:0000313|Proteomes:UP000002213};
RX   PubMed=21304636; DOI=10.4056/sigs.21137;
RA   Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA   Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D., Goodwin L.,
RA   Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavromatis K.,
RA   Chen A., Palaniappan K., Hauser L., Chang Y.J., Jeffries C.C., Brettin T.,
RA   Detter J.C., Han C., Chain P., Tindall B.J., Bristow J., Eisen J.A.,
RA   Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL   Stand. Genomic Sci. 1:46-53(2009).
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DR   EMBL; CP001630; ACU38638.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6WPD6; -.
DR   STRING; 446462.Amir_4811; -.
DR   KEGG; ami:Amir_4811; -.
DR   eggNOG; COG5635; Bacteria.
DR   HOGENOM; CLU_300313_0_0_11; -.
DR   OrthoDB; 135105at2; -.
DR   Proteomes; UP000002213; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00267; ABC_ATPase; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR46844; SLR5058 PROTEIN; 1.
DR   PANTHER; PTHR46844:SF1; SLR5058 PROTEIN; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002213};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        23..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        56..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        81..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          201..330
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   1067 AA;  118399 MW;  6FD87244EC4776B8 CRC64;
     MKFGLLTWLP EENHPARNVL EGLSWVSAII AVVPTALLAI GWAWRTNPPN DGERVTPVRV
     GPPIIGVVPA LLVLLSGSPW WALAVFFLVE AAVFASGLLG ALGQVLQERI TDWTRRTITS
     GMVRFGAQYR AFMLRSLRTM VEEGPPTTGF LRPELDDVFV NVTLEYQAPQ RVATGLVGGL
     DPDTLEEGHV LDDFLDKEQP EVLAVTGAPG SGKTTLLRKA ARDICKSTRG KRKRRSVPLL
     LYLRDHAETI AANPEVPVFT LLHKQLKRAG LTASDSWFER RLKSGQCVVL LDGLDEVARQ
     DDRRAVSAWV ALQISVYYKN HFVITSRPDG YKSAKIENAT VLAVQQFTDG QIEKFVHSWY
     RTIERRSSSD TSDLEHVVKT KASDLLERLN QNVNLRALTV NPLLLTMIVN VHRFRGALPG
     SRVDLYGEIC EVMLWRRQEA KKLAVEMSGQ KKAALLRGLA YRMMKNDAPS MSRVEVLAQI
     KPGMQRMSRD VTAEGFLADV TSNGLIVESE NGLYAFAHLT FQEYLAAEHI RDKGLVKELA
     NHVGSSWWRE TTLLYAAKSD ADAIVRACLD RGSTAALLLA FDCADQDSEL APELVDRMNA
     FLESAHEPGA SSDQCLLAAG VLAGRHLGEL VRTSTESYVC PSPITNRIYW LYQRGQQDHD
     AYRLSNVESG GEEAVLGVRL EDALAFTRWL NTVFTENKTF RLVEEDEVAD HAITSARSTR
     RGATSDYSVW FRRKEQNAFG LLPPPGGEHP YHLRTEVLLE RTKADVLDHA PDLVRLALLL
     AFRRAEQASL GLDLMQNRIK KAAESNTRLR QSDVDVKLSN RRRELSSGPR ELTQNLEGER
     ELITSLGLEP ALDTILGVLN AIIQSPRASR VKHLQHGRRL AKELAGELSP EFTRTLTTAE
     NGVRPDVSEQ FTGRALKSIM NRALVGGAVR EPWMTRLAED LVLLAAGSDD FVVAPPDTLA
     DRMDLTHTAL VAFSQSEDVE NFLPWALKAS SALQDLAVPI LRYEQPVDRG PASLIRFSAL
     LLAAETGVER RGVLSKSFLE IAAGITLMEQ HHEGTRKRNE TIVLARA
//