ID C6WS62_ACTMD Unreviewed; 402 AA.
AC C6WS62;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Mandelate racemase/muconate lactonizing protein {ECO:0000313|EMBL:ACU38882.1};
GN OrderedLocusNames=Amir_5060 {ECO:0000313|EMBL:ACU38882.1};
OS Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064
OS / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinosynnema.
OX NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU38882.1, ECO:0000313|Proteomes:UP000002213};
RN [1] {ECO:0000313|EMBL:ACU38882.1, ECO:0000313|Proteomes:UP000002213}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 /
RC NRRL B-12336 / IMRU 3971 / 101 {ECO:0000313|Proteomes:UP000002213};
RX PubMed=21304636; DOI=10.4056/sigs.21137;
RA Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D., Goodwin L.,
RA Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavromatis K.,
RA Chen A., Palaniappan K., Hauser L., Chang Y.J., Jeffries C.C., Brettin T.,
RA Detter J.C., Han C., Chain P., Tindall B.J., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL Stand. Genomic Sci. 1:46-53(2009).
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DR EMBL; CP001630; ACU38882.1; -; Genomic_DNA.
DR RefSeq; WP_015803769.1; NC_013093.1.
DR AlphaFoldDB; C6WS62; -.
DR STRING; 446462.Amir_5060; -.
DR KEGG; ami:Amir_5060; -.
DR eggNOG; COG4948; Bacteria.
DR HOGENOM; CLU_030273_6_1_11; -.
DR OrthoDB; 5241672at2; -.
DR Proteomes; UP000002213; Chromosome.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR GO; GO:0009063; P:amino acid catabolic process; IEA:InterPro.
DR CDD; cd03322; RspA; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR034589; D-mannonate_dehydratase-like.
DR InterPro; IPR034593; DgoD-like.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR013341; Mandelate_racemase_N_dom.
DR PANTHER; PTHR48080; D-GALACTONATE DEHYDRATASE-RELATED; 1.
DR PANTHER; PTHR48080:SF6; STARVATION-SENSING PROTEIN RSPA; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF02746; MR_MLE_N; 1.
DR SFLD; SFLDS00001; Enolase; 1.
DR SFLD; SFLDG00033; mannonate_dehydratase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR PROSITE; PS00908; MR_MLE_1; 1.
DR PROSITE; PS00909; MR_MLE_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002213}.
FT DOMAIN 130..257
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
SQ SEQUENCE 402 AA; 44437 MW; 4AF0482C08421B9F CRC64;
MSTIERAEVL IASPGRNFVT LRITTSDGVT GLGDATLNGR ELAVASYLRD HVVPLLIGRD
PARIEDTWQY LYRGAYWRRG PVTMTAIAAV DTALWDIKGK VADLPVYQLL GGRSRDGVMV
YSHASGADTA ELLDDVARFL DLGYLAVRAQ AAVPNVKGTY GVRKGAVYEP AATALPDEQP
WNTPAYLDFA PTYLAAVRER FGFGFHLLHD VHHRLTPIEA ARFGKSVEDL RLFWMEDPTP
AENQEAFRLI RRHTTTPIAV GENLSSIWDV QHLITEQLID YVRTTVVHAG GITHLRRIFD
LAALYQVRTG SHGATDLSPV SMAAAVHVDI SVPNFGIQEH MGHTPEVAEV FRSDVRFENG
MLHPSDAPGL GVEYDDDAAA RFPYDPRYLP VARLADGSMH DW
//
