ID C6WW61_METML Unreviewed; 1064 AA.
AC C6WW61;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor {ECO:0000313|EMBL:ACT48160.1};
GN OrderedLocusNames=Mmol_1254 {ECO:0000313|EMBL:ACT48160.1};
OS Methylotenera mobilis (strain JLW8 / ATCC BAA-1282 / DSM 17540).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Methylophilaceae; Methylotenera.
OX NCBI_TaxID=583345 {ECO:0000313|EMBL:ACT48160.1, ECO:0000313|Proteomes:UP000002742};
RN [1] {ECO:0000313|Proteomes:UP000002742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JLW8 / ATCC BAA-1282 / DSM 17540
RC {ECO:0000313|Proteomes:UP000002742};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., LaButti K.M., Clum A., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Kayluzhnaya M., Chistoserdova L.;
RT "Complete sequence of Methylotenera mobilis JLW8.";
RL Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACT48160.1, ECO:0000313|Proteomes:UP000002742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JLW8 / ATCC BAA-1282 / DSM 17540
RC {ECO:0000313|Proteomes:UP000002742};
RX PubMed=21622745; DOI=10.1128/JB.00404-11;
RA Lapidus A., Clum A., Labutti K., Kaluzhnaya M.G., Lim S., Beck D.A.,
RA Glavina Del Rio T., Nolan M., Mavromatis K., Huntemann M., Lucas S.,
RA Lidstrom M.E., Ivanova N., Chistoserdova L.;
RT "Genomes of three methylotrophs from a single niche uncover genetic and
RT metabolic divergence of Methylophilaceae.";
RL J. Bacteriol. 193:3757-3764(2011).
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; CP001672; ACT48160.1; -; Genomic_DNA.
DR RefSeq; WP_015832195.1; NC_012968.1.
DR AlphaFoldDB; C6WW61; -.
DR STRING; 583345.Mmol_1254; -.
DR KEGG; mmb:Mmol_1254; -.
DR eggNOG; COG0840; Bacteria.
DR HOGENOM; CLU_000445_107_20_4; -.
DR OrthoDB; 9813966at2; -.
DR Proteomes; UP000002742; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd11386; MCP_signal; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.20.120.1530; -; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR024478; HlyB_4HB_MCP.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43531:SF14; METHYL-ACCEPTING CHEMOTAXIS PROTEIN I-RELATED; 1.
DR PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR Pfam; PF12729; 4HB_MCP_1; 1.
DR Pfam; PF18947; HAMP_2; 3.
DR Pfam; PF00015; MCPsignal; 1.
DR Pfam; PF08447; PAS_3; 1.
DR PRINTS; PR00260; CHEMTRNSDUCR.
DR SMART; SM00283; MA; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50112; PAS; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002742};
KW Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 160..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..76
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 671..723
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 774..1003
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT COILED 793..830
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1064 AA; 116866 MW; 18654CAF3648CA0D CRC64;
MKINMPVTQR ELELNSTHQL VSKTDLKGRI TFVNRDFIRV SGFAEDELIG QSHNIVRHPD
MPPEAFDDLW STVKSGKPWI GIVKNRCKNG DHYWVEAVVT PVKENGEVSG YISVRKKASL
EQIQGALNYH RYLKEHHSWL EGVMTKVNNF KRNFSLKARI VCIFMAVALT CFSLGVNGLY
GIQYSNERLS TVYNDRVVPL QQLKTVADMY AVNIVDTSHK VRNGNITWTQ AEQNVDDAIK
AVDKNWEAYT NTYLVAEEQK LISETKPLFV QANLATAKLK EILKARDEAS ITEFTVNQLY
PAIEPLSEKI SQLTLLQLDI AAKEFNQAQE NYILKRNLNI LFILLGLLIT GFLGWQLYHA
IMPRIRMAIE YLMASAQGED HDSVLRTGHR DEMTDVMDAY RALKTRMDFN YTDTLAGVDR
IKSALDNASI PVTVGNENNK LIYMNKAGFA LWEKMSANIK KLHPDFAVDK LIGGTLGKYI
ESEEDRASYV AELKGSKVLN TAMGGRHLRL TFNPVHNAEG HYLGRMIQWD DRTEELIAEQ
SIARLIEQTV AGDLTNRIDA TQYPEGFLKE ISEGMNKLLE AVIGPLNMAA NYVDSLSKGV
IPVEITKDYK GDFNIIKNNL NACGLAIKSL VADGNLLAQA AEAGDLTARA DASKHLGEYR
KVIEGLNATL DAIVEPLNMA ANSVEDIARG DIPQQITSRY NGDFNKIKDN LNTCFSSINA
LVADARKLSD AAAEGDVLVR ADADRHQGDY RKIVNGMNET LEMIVTPIVT VQQSVETINT
AAREIAQGNA DLSRRTEDQA ASLEKTAASM EELSSTVKQN ADNAKQANQL ASAASGVAVK
GGVAVSAVVN TMAEINESAK KIEDIISVID GIAFQTNILA LNAAVEAARA GEQGRGFAVV
AGEVRNLAQR SASAAKEIKE LITNSVNKTA EGTKQVETAG ETMQEIVSSV KRVSDIIGEI
SAASQEQSAG IEQVNEAIMK MDDVTQQNTA LVEEAAAAAE SMMEQADELM NAISVFKLGG
GNESRVAIRP VSKVAVSKVA QSTRPIPVKL SVKTNSDDGD WEEF
//
