ID C6X273_FLAB3 Unreviewed; 729 AA.
AC C6X273;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Phytochrome, two-component sensor histidine kinase {ECO:0000313|EMBL:ACU08536.1};
DE EC=2.7.3.- {ECO:0000313|EMBL:ACU08536.1};
GN OrderedLocusNames=FIC_02099 {ECO:0000313|EMBL:ACU08536.1};
OS Flavobacteriaceae bacterium (strain 3519-10).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae.
OX NCBI_TaxID=531844 {ECO:0000313|EMBL:ACU08536.1, ECO:0000313|Proteomes:UP000001512};
RN [1] {ECO:0000313|EMBL:ACU08536.1, ECO:0000313|Proteomes:UP000001512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3519-10 {ECO:0000313|EMBL:ACU08536.1,
RC ECO:0000313|Proteomes:UP000001512};
RX PubMed=18622572; DOI=10.1007/s00792-008-0178-2;
RA Raymond J.A., Christner B.C., Schuster S.C.;
RT "A bacterial ice-binding protein from the Vostok ice core.";
RL Extremophiles 12:713-717(2008).
CC -!- SIMILARITY: In the N-terminal section; belongs to the phytochrome
CC family. {ECO:0000256|ARBA:ARBA00006402}.
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DR EMBL; CP001673; ACU08536.1; -; Genomic_DNA.
DR AlphaFoldDB; C6X273; -.
DR STRING; 531844.FIC_02099; -.
DR KEGG; fba:FIC_02099; -.
DR eggNOG; COG4251; Bacteria.
DR HOGENOM; CLU_000445_50_1_10; -.
DR OrthoDB; 9766459at2; -.
DR Proteomes; UP000001512; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR GO; GO:0009584; P:detection of visible light; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.270; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013654; PAS_2.
DR InterPro; IPR016132; Phyto_chromo_attachment.
DR InterPro; IPR001294; Phytochrome.
DR InterPro; IPR013515; Phytochrome_cen-reg.
DR InterPro; IPR043150; Phytochrome_PHY_sf.
DR PANTHER; PTHR42878:SF13; OSMOLARITY TWO-COMPONENT SYSTEM PROTEIN SSK1; 1.
DR PANTHER; PTHR42878; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08446; PAS_2; 1.
DR Pfam; PF00360; PHY; 1.
DR PRINTS; PR01033; PHYTOCHROME.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50046; PHYTOCHROME_2; 1.
PE 3: Inferred from homology;
KW Chromophore {ECO:0000256|ARBA:ARBA00022991};
KW Kinase {ECO:0000313|EMBL:ACU08536.1};
KW Photoreceptor protein {ECO:0000256|ARBA:ARBA00022543};
KW Receptor {ECO:0000256|ARBA:ARBA00022543};
KW Reference proteome {ECO:0000313|Proteomes:UP000001512};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transferase {ECO:0000313|EMBL:ACU08536.1}.
FT DOMAIN 136..278
FT /note="Phytochrome chromophore attachment site"
FT /evidence="ECO:0000259|PROSITE:PS50046"
FT DOMAIN 519..729
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 729 AA; 82066 MW; A8D889B3856C1C09 CRC64;
MNLADCHEEK IHVSGHIQDF GYLIGLDPDT QFIRLFSQNI FEIIPVDESF IGRTMQDAPE
VFGALLKSVV LSNLDFATMK DVDVFLDKIE IGNATFHLTI YRYTGIIFLE LEEMSESFQQ
KTFVSKKYES ISNAPTSGEI WEQLLNVVAE TCDYDRVMIY RFLDDGSGKV IAEKVKNEVD
SFLHLHYPES DIPRQARELY MKKRKRIFSN VYSTPVPIIS ALEKPVDLTY STLRAMSPVH
GQYLKNSGVS SSFSTSIVVG NKLWGLVTCQ NTEPKHIDLV NRIRCEVFTV IASNAYTSYK
SQQSLKDSAE LDSKINLLKS RLQKHENLND SLFSNIDEMR KYPSADGLAI VIADEIRTSG
TVPDDANIMK IVRYARENPP QNFYFTNDFG NVSDGKLGNI PNAAGVIFGF TDDKRNELLI
WFRGAIDTQV LWAGNPSKET SETILNGDQH YVMSPRKSFA TYIESIKGKS EPWKNRDIFA
AKKVVAAILE TTYSQFKKVQ DLYEELKNLN EELDSFSYTI SHDLGTPLTV MKLNAQLLER
AHHDNPEVGK RVASILQEIL GMEDMMRGVL QLSRAKSTEI VVKEVETAKI IRKICLDAQL
TLSQTTEIII GKTPSVLADE TMVMQAFLNI IGNAVKYSSK SAMPKVEIHG AEQRDQVVYT
VKDNGIGIPA EAQEKMFKIF NRMDNAKGFQ GNGVGLSIVF RIMGRLGGSI SYQSKEGEGT
TFTLIFRKP
//
