ID C6XJK2_HIRBI Unreviewed; 814 AA.
AC C6XJK2;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Hbal_1609 {ECO:0000313|EMBL:ACT59297.1};
OS Hirschia baltica (strain ATCC 49814 / DSM 5838 / IFAM 1418).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomonadales;
OC Hyphomonadaceae; Hirschia.
OX NCBI_TaxID=582402 {ECO:0000313|EMBL:ACT59297.1, ECO:0000313|Proteomes:UP000002745};
RN [1] {ECO:0000313|Proteomes:UP000002745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49814 / DSM 5838 / IFAM 1418
RC {ECO:0000313|Proteomes:UP000002745};
RX PubMed=21705585; DOI=10.1128/JB.05453-11;
RG US DOE Joint Genome Institute;
RA Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.;
RT "Genome sequences of eight morphologically diverse alphaproteobacteria.";
RL J. Bacteriol. 193:4567-4568(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP001678; ACT59297.1; -; Genomic_DNA.
DR RefSeq; WP_015827447.1; NC_012982.1.
DR AlphaFoldDB; C6XJK2; -.
DR STRING; 582402.Hbal_1609; -.
DR KEGG; hba:Hbal_1609; -.
DR eggNOG; COG2203; Bacteria.
DR eggNOG; COG3829; Bacteria.
DR eggNOG; COG4251; Bacteria.
DR HOGENOM; CLU_000445_114_44_5; -.
DR OrthoDB; 9795133at2; -.
DR Proteomes; UP000002745; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43102:SF2; GAF DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43102; SLR1143 PROTEIN; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF08448; PAS_4; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ACT59297.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002745};
KW Transferase {ECO:0000313|EMBL:ACT59297.1}.
FT DOMAIN 536..587
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 598..814
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 814 AA; 90575 MW; 961FF48E12506BB1 CRC64;
MVDDKNEQTR LATLAALKIL DTKPEAQYDN VTALAAEMFD VPIALVSLVD ENRQWFKSNC
GLDGVTETAR DISFCQHAIK STNVMVVENA IEDEKYDQNP LVLGEPSIRF YAGAPLITEE
GHALGTLCLI DRKPRKFSAQ EQALLVRLAT TIRDMIVKNT LEHEIIELAK AARKESEISR
SIYDASEAVI LRLEAVFNEQ GIVSDFTLLG ANAALELNTG QKLESLIGNK MLDLFPNIKE
VGLFALYSKV VKTGKSETVE IEYTDDTISA WFRVKAEPCG VNGLTVASTP ISQRKNFEAT
VKALKAISPL AHSDPTKYLE ELLELGRRTF HATDGFVSNI QDKKYLVKAY VGEMEGLAAG
VELALPDTIC AAVVEEQTAL SFDDLQSNET KCHPAVPQNE FASYLGAPIF VDEEFYGTIS
FVSDVKRSSP FPTTDLELLS IIAASIGHAI ESQKAFEKYA RLNDELRMVL DNVPARIWYK
DNNNKILRAN KAAVLSVGLN DPLEVEGVAT EDLFPEIAEK YLQDDLSVIE SGKPRRNIVE
SYAPTNGIEG WISTDKIPMI GEDGNTTILA VATDITELKL KEEQLSRLNE SLSDFAFVAS
HDLQAPLRQS AMFSELFADE LKEHEIVLPT LAAEYFDEME DGLRRMRVMV RSLYDMFKLD
SEKIKKKITD FEQIVVQARK QVNSEVEAVG ANIEIGDFFQ HNVNEELLVQ VIQNLVVNAC
KYSMADQLNI KIHSQIDVIN RQKCIIVEDN GVGIAEQFQK KIFEPFKRLH HGKTIEGAGI
GLALCKKIMA LHDGDLYVDS SFKDGAKFVM AFGY
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