ID C6XQ37_HIRBI Unreviewed; 400 AA.
AC C6XQ37;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE SubName: Full=TIR protein {ECO:0000313|EMBL:ACT58554.1};
GN OrderedLocusNames=Hbal_0860 {ECO:0000313|EMBL:ACT58554.1};
OS Hirschia baltica (strain ATCC 49814 / DSM 5838 / IFAM 1418).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomonadales;
OC Hyphomonadaceae; Hirschia.
OX NCBI_TaxID=582402 {ECO:0000313|EMBL:ACT58554.1, ECO:0000313|Proteomes:UP000002745};
RN [1] {ECO:0000313|Proteomes:UP000002745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49814 / DSM 5838 / IFAM 1418
RC {ECO:0000313|Proteomes:UP000002745};
RX PubMed=21705585; DOI=10.1128/JB.05453-11;
RG US DOE Joint Genome Institute;
RA Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.;
RT "Genome sequences of eight morphologically diverse alphaproteobacteria.";
RL J. Bacteriol. 193:4567-4568(2011).
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DR EMBL; CP001678; ACT58554.1; -; Genomic_DNA.
DR RefSeq; WP_015826704.1; NC_012982.1.
DR AlphaFoldDB; C6XQ37; -.
DR STRING; 582402.Hbal_0860; -.
DR KEGG; hba:Hbal_0860; -.
DR eggNOG; COG2815; Bacteria.
DR HOGENOM; CLU_688453_0_0_5; -.
DR OrthoDB; 7055795at2; -.
DR Proteomes; UP000002745; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR Pfam; PF13676; TIR_2; 1.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002745};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 257..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..130
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 151..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..174
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..189
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 400 AA; 44070 MW; EAE948DF9BE3C27F CRC64;
MDYDIFLSYR RVDQELARAL VTALEARGVG VWWDQKIEGG VDWRDAIVEN LISSDMLVIL
FSEECNNSKQ LKKELALADD MDKDVIPVLI EDTKPKGHFL YEMAARNWIQ IHPNPENKIN
ELADRLTLLA EASPGGLAGT KPEPIPEAAP VEAAAQPALS QQDAVDTNQP DIPQQTVTTP
PPKTPASAPP ASPFAGINPN DLVARREALK REEALLEIAE KKAKLKAGGA KPVAKKEAAS
AQSKTSRGKV KKQYRNFLPF KWIDLILLSP ILYFIVEETG GGFDRLDFTD ISEMTEFMAM
ISVSLAGVGA LVFPIRYYMR NLRMKEAAKE YAKSSLALYA LLWLSGLTFA INEGEIGEVV
GVCLGFGGLW VAFGVGAFAL YGLMHFQRSV RNFKSNVDKI
//
