ID C6XY45_PEDHD Unreviewed; 397 AA.
AC C6XY45;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:ACU04463.1};
GN OrderedLocusNames=Phep_2259 {ECO:0000313|EMBL:ACU04463.1};
OS Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457
OS / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3).
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=485917 {ECO:0000313|EMBL:ACU04463.1, ECO:0000313|Proteomes:UP000000852};
RN [1] {ECO:0000313|EMBL:ACU04463.1, ECO:0000313|Proteomes:UP000000852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 /
RC NCIMB 9290 / NRRL B-14731 / HIM 762-3
RC {ECO:0000313|Proteomes:UP000000852};
RX PubMed=21304637; DOI=10.4056/sigs.22138;
RA Han C., Spring S., Lapidus A., Del Rio T.G., Tice H., Copeland A.,
RA Cheng J.F., Lucas S., Chen F., Nolan M., Bruce D., Goodwin L., Pitluck S.,
RA Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.C., Saunders E., Chertkov O.,
RA Brettin T., Goker M., Rohde M., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P., Detter J.C.;
RT "Complete genome sequence of Pedobacter heparinus type strain (HIM 762-
RT 3).";
RL Stand. Genomic Sci. 1:54-62(2009).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP001681; ACU04463.1; -; Genomic_DNA.
DR AlphaFoldDB; C6XY45; -.
DR STRING; 485917.Phep_2259; -.
DR KEGG; phe:Phep_2259; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_2_1_10; -.
DR Proteomes; UP000000852; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF23; MULTIDRUG RESISTANCE PROTEIN MEXA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000000852}.
FT DOMAIN 76..301
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 153..180
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 397 AA; 42645 MW; 595342852E8AF452 CRC64;
MNNNLFYPSQ LNTVKLSIHV MKTTILLAAL FLMGCADKTP QAAAPAPPAL PVASITTGSE
TTFQDYPASI EGTVNVEIRP QVSGTLEKVY IDEGAFVNSG QPIFKINEQP YRAALNNALA
SQHSAEASLI NAQLEVERLT PLVQNKVISE FQLKSAKATA QVAKANIEQA KANVATASIN
LGYTLIKAPV SGYIGRLLKK QGSLVTATDA EALTNLSDVH DVHVYFALGE KDFVNFKDQY
PGQTLNEKIK QLPAVKLILA DNTEYARSGK IDVIDGQFDK TTGAITVRAK FPNPDGLLRS
GNTGKIRLSL QHNNALVVPQ VATIEVQDKV FVFALADSNK VKKQAITIIG KAGNNYLVKD
GIKAGDQIVL SGLDRLQEGV VIAPQKATDK VVAITKK
//
