ID C6Y3V4_PEDHD Unreviewed; 555 AA.
AC C6Y3V4;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Type I phosphodiesterase/nucleotide pyrophosphatase {ECO:0000313|EMBL:ACU03383.1};
GN OrderedLocusNames=Phep_1165 {ECO:0000313|EMBL:ACU03383.1};
OS Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457
OS / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3).
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=485917 {ECO:0000313|EMBL:ACU03383.1, ECO:0000313|Proteomes:UP000000852};
RN [1] {ECO:0000313|EMBL:ACU03383.1, ECO:0000313|Proteomes:UP000000852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 /
RC NCIMB 9290 / NRRL B-14731 / HIM 762-3
RC {ECO:0000313|Proteomes:UP000000852};
RX PubMed=21304637; DOI=10.4056/sigs.22138;
RA Han C., Spring S., Lapidus A., Del Rio T.G., Tice H., Copeland A.,
RA Cheng J.F., Lucas S., Chen F., Nolan M., Bruce D., Goodwin L., Pitluck S.,
RA Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.C., Saunders E., Chertkov O.,
RA Brettin T., Goker M., Rohde M., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P., Detter J.C.;
RT "Complete genome sequence of Pedobacter heparinus type strain (HIM 762-
RT 3).";
RL Stand. Genomic Sci. 1:54-62(2009).
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DR EMBL; CP001681; ACU03383.1; -; Genomic_DNA.
DR RefSeq; WP_012781327.1; NZ_AQGK01000001.1.
DR AlphaFoldDB; C6Y3V4; -.
DR STRING; 485917.Phep_1165; -.
DR KEGG; phe:Phep_1165; -.
DR eggNOG; COG1524; Bacteria.
DR HOGENOM; CLU_034095_0_0_10; -.
DR OrthoDB; 9766127at2; -.
DR Proteomes; UP000000852; Chromosome.
DR GO; GO:0004035; F:alkaline phosphatase activity; IEA:InterPro.
DR CDD; cd16016; AP-SPAP; 1.
DR Gene3D; 3.30.1360.150; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR026263; Alkaline_phosphatase_prok.
DR InterPro; IPR002591; Phosphodiest/P_Trfase.
DR PANTHER; PTHR10151:SF120; BIS(5'-ADENOSYL)-TRIPHOSPHATASE; 1.
DR PANTHER; PTHR10151; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE; 1.
DR Pfam; PF01663; Phosphodiest; 1.
DR PIRSF; PIRSF031924; Pi-irrepressible_AP; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|PIRSR:PIRSR031924-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000000852};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..555
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002973655"
FT ACT_SITE 90
FT /note="Phosphothreonine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR031924-50"
FT BINDING 111
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
FT BINDING 172..174
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
SQ SEQUENCE 555 AA; 62159 MW; 96EDA2132AC7412B CRC64;
MKRIYLLFAA LILFTQVSTA QKKAIKNESK KENPGTLNRP KLVVGLVIDQ MRWDYLYRYY
SRYTNGGFKR LINEGFSAEN TFIPYTPTYT ACGHASIYTG SVPSINGIIG NDWYDPQLQR
SVYCAEDTTV KTVGSNTAAG LMSPKNMLVT TITDELRLAT NFKSKVIGIS LKDRGSILPA
GHSANAAYWF DGQTGDWISS TYYMNQLPAW MQDYNKKKEA DKFFAQNWNT LYPIDSYTQS
TSDNKVYERK NRGEENPVFP HPLKLYMGKN YEMIKSTPYG NTITLDLAKQ AIAAENLGQN
NTTDFLAVSC SATDYVGHQY GPNSIEAEDT YLRLDKDLEA FFNYLDNKLG KGNYLFFLSA
DHGAAHVAGF MTENKLPGGT FSDANIIKTL NAQFEEKFKV KKAIITGMNS QIVFNHDAIK
KANADYEQMK TMTIDYLKKQ PGVMNAVDLS KLSSTTLPER LKMAVTNGYN ARRSGDIYYF
LQSGYFSGGS TGTTHGSWNP YDSHIPCVFM GWKVKAGKTN KTHYMTDISA TLAAMLQIQM
PSGCVGEPIT ELTHQ
//
