ID   C7BA82_DROMO            Unreviewed;       219 AA.
AC   C7BA82;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=trypsin {ECO:0000256|ARBA:ARBA00038868};
DE            EC=3.4.21.4 {ECO:0000256|ARBA:ARBA00038868};
DE   Flags: Fragment;
OS   Drosophila mojavensis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7230 {ECO:0000313|EMBL:ACT21126.1};
RN   [1] {ECO:0000313|EMBL:ACT21126.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Catalina Island-7 {ECO:0000313|EMBL:ACT21126.1};
RX   PubMed=19204376; DOI=10.1534/genetics.108.099044;
RA   Kelleher E.S., Markow T.A.;
RT   "Duplication, selection and gene conversion in a Drosophila mojavensis
RT   female reproductive protein family.";
RL   Genetics 181:1451-1465(2009).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.; EC=3.4.21.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00036320};
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DR   EMBL; FJ839200; ACT21126.1; -; Genomic_DNA.
DR   AlphaFoldDB; C7BA82; -.
DR   MEROPS; S01.B79; -.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00190; Tryp_SPc; 1.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR001314; Peptidase_S1A.
DR   InterPro; IPR001254; Trypsin_dom.
DR   InterPro; IPR018114; TRYPSIN_HIS.
DR   InterPro; IPR033116; TRYPSIN_SER.
DR   PANTHER; PTHR24264:SF15; RIKEN CDNA 2210010C04 GENE; 1.
DR   PANTHER; PTHR24264; TRYPSIN-RELATED; 1.
DR   Pfam; PF00089; Trypsin; 1.
DR   PRINTS; PR00722; CHYMOTRYPSIN.
DR   SMART; SM00020; Tryp_SPc; 1.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR   PROSITE; PS50240; TRYPSIN_DOM; 1.
DR   PROSITE; PS00134; TRYPSIN_HIS; 1.
DR   PROSITE; PS00135; TRYPSIN_SER; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU363034};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU363034};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825,
KW   ECO:0000256|RuleBase:RU363034}.
FT   DOMAIN          16..219
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000259|PROSITE:PS50240"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ACT21126.1"
FT   NON_TER         219
FT                   /evidence="ECO:0000313|EMBL:ACT21126.1"
SQ   SEQUENCE   219 AA;  24461 MW;  5DC6870EDE8A7711 CRC64;
     SFNELFRQPP RIDGRIVGGQ PINITDAPYQ ISLQLVLPLS LIHDCGGSLI SKEWILTAAH
     CTYGRKTNQL RVRLGSSESK RNGQLLRIKK IVNHEKYNHV TTDYDFSLLQ LQEPIEFDET
     KQAVKLPKQG QEFKDGEMCY VSGWGKTLNP EESSKWLRQV KVPLYNQKEC RKRNLLVGIV
     TDNMICAGYM QGGKDACQGD SGGPLVNGNG VLVGVVSWG
//