ID C7BLS4_PHOAA Unreviewed; 446 AA.
AC C7BLS4;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Pmba protein, involved in the maturation of antibiotic {ECO:0000313|EMBL:CAQ85780.1};
GN Name=pmbA {ECO:0000313|EMBL:CAQ85780.1};
GN OrderedLocusNames=PAU_03692 {ECO:0000313|EMBL:CAQ85780.1};
OS Photorhabdus asymbiotica subsp. asymbiotica (strain ATCC 43949 / 3105-77)
OS (Xenorhabdus luminescens (strain 2)).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Photorhabdus.
OX NCBI_TaxID=553480 {ECO:0000313|EMBL:CAQ85780.1, ECO:0000313|Proteomes:UP000002747};
RN [1] {ECO:0000313|EMBL:CAQ85780.1, ECO:0000313|Proteomes:UP000002747}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43949 / 3105-77 {ECO:0000313|Proteomes:UP000002747};
RX PubMed=19583835; DOI=10.1186/1471-2164-10-302;
RA Wilkinson P., Waterfield N.R., Crossman L., Corton C.,
RA Sanchez-Contreras M., Vlisidou I., Barron A., Bignell A., Clark L.,
RA Ormond D., Mayho M., Bason N., Smith F., Simmonds M., Churcher C.,
RA Harris D., Thompson N.R., Quail M., Parkhill J., ffrench-Constant R.H.;
RT "Comparative genomics of the emerging human pathogen Photorhabdus
RT asymbiotica with the insect pathogen Photorhabdus luminescens.";
RL BMC Genomics 10:302-302(2009).
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
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DR EMBL; FM162591; CAQ85780.1; -; Genomic_DNA.
DR AlphaFoldDB; C7BLS4; -.
DR STRING; 291112.PAU_03692; -.
DR KEGG; pay:PAU_03692; -.
DR eggNOG; COG0312; Bacteria.
DR Proteomes; UP000002747; Chromosome.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR047657; PmbA.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR43421; METALLOPROTEASE PMBA; 1.
DR PANTHER; PTHR43421:SF1; METALLOPROTEASE PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022670};
KW Protease {ECO:0000256|ARBA:ARBA00022670}.
FT DOMAIN 32..96
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 124..230
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 238..445
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 446 AA; 47971 MW; A67E361A8BD07EEB CRC64;
MKIIDQIAEQ RKQLENAVSQ ALELAKAGCD AAEVAVNKTT GIGVSTRFGE IENVEFNSDG
ALGITVYHQQ RKGSASSTDL SPDAIARTVQ AAIDIARYTS QDPCAGPADK ALLAFEVPDL
DLFHPTELDA DKAIELAARA EQAALQADKR ITNTEGGSFN SHYGIRVFGN SHGMLQSYCS
SRHSMSSCVV AEVDGDMERD YAYTISRRFE DLKSPEWVGQ ECARRVLSRL SPRKLPTMKA
PVLFAAEVAT GLFGHLVGAI SGSSIYRKSS FLLDHLGKQI LPSWLTIEER PHLLAGLASS
PFDSEGVCTS NRDIIKDGVL QTWLLTSYSA RKLGMASTGH AGGIHNWCIA GQGQDFTGLL
RQMGSGLVVT ELMGQGVSAI TGDYSRGAAG FWVENGEIQY PVSEITIAGN LKDMWANMVT
IGDDIETRSN IQCGSVLLSE MSIAGQ
//
