ID C7BXL7_HELPB Unreviewed; 232 AA.
AC C7BXL7;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Methyltransferase {ECO:0000256|RuleBase:RU362026};
DE EC=2.1.1.- {ECO:0000256|RuleBase:RU362026};
GN Name=hpy99VM {ECO:0000313|EMBL:CAX28602.1};
GN OrderedLocusNames=HELPY_0045 {ECO:0000313|EMBL:CAX28602.1};
OS Helicobacter pylori (strain B38).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=592205 {ECO:0000313|EMBL:CAX28602.1, ECO:0000313|Proteomes:UP000000313};
RN [1] {ECO:0000313|EMBL:CAX28602.1, ECO:0000313|Proteomes:UP000000313}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B38 {ECO:0000313|EMBL:CAX28602.1,
RC ECO:0000313|Proteomes:UP000000313};
RX PubMed=20537153; DOI=10.1186/1471-2164-11-368;
RA Thiberge J.M., Boursaux-Eude C., Lehours P., Dillies M.A., Creno S.,
RA Coppee J.Y., Rouy Z., Lajus A., Ma L., Burucoa C., Ruskone-Foumestraux A.,
RA Courillon-Mallet A., De Reuse H., Boneca I.G., Lamarque D., Megraud F.,
RA Delchier J.C., Medigue C., Bouchier C., Labigne A., Raymond J.;
RT "From array-based hybridization of Helicobacter pylori isolates to the
RT complete genome sequence of an isolate associated with MALT lymphoma.";
RL BMC Genomics 11:368-368(2010).
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594, ECO:0000256|RuleBase:RU362026}.
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DR EMBL; FM991728; CAX28602.1; -; Genomic_DNA.
DR RefSeq; WP_000614620.1; NC_012973.1.
DR AlphaFoldDB; C7BXL7; -.
DR REBASE; 21312; M1.HpyB38ORF45P.
DR KEGG; hpb:HELPY_0045; -.
DR HOGENOM; CLU_024927_5_1_7; -.
DR Proteomes; UP000000313; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR001091; RM_Methyltransferase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR PANTHER; PTHR13370:SF33; TYPE II METHYLTRANSFERASE M.MJAV; 1.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR PRINTS; PR00508; S21N4MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:CAX28602.1};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CAX28602.1}.
FT DOMAIN 23..227
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
SQ SEQUENCE 232 AA; 27152 MW; 7D118602A0730284 CRC64;
MIQIHHADAF EIIKDFYQQN LKVDAIITDP PYNISVKNNF STLKSAKRQG IDFGEWDKNF
RLLEWIKRYA PLINPNGCMV IFCSYRFISY IADFLEENGF VVKDFIQWVK TNPMPRNIHR
RYVQDTEFAL WAVKKKAKWV FNKPKNEKYL RPLILKSPVV SGLEKTKHPT QKSLALMEKI
ISIHTNPNDI VLDPFMGSGT TGLACKNLKR NFIGIESEKE YFQTAKKRLN LF
//
