ID C7C7S5_METED Unreviewed; 381 AA.
AC C7C7S5;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Beta-ketoacyl-acyl-carrier-protein synthase (FabF-like) {ECO:0000313|EMBL:CAX27201.1};
DE EC=2.3.1.41 {ECO:0000313|EMBL:CAX27201.1};
GN ORFNames=METD_I5597 {ECO:0000313|EMBL:CAX27201.1};
OS Methylorubrum extorquens (strain DSM 6343 / CIP 106787 / DM4)
OS (Methylobacterium extorquens).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylorubrum.
OX NCBI_TaxID=661410 {ECO:0000313|EMBL:CAX27201.1, ECO:0000313|Proteomes:UP000008070};
RN [1] {ECO:0000313|Proteomes:UP000008070}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6343 / CIP 106787 / DM4
RC {ECO:0000313|Proteomes:UP000008070};
RX PubMed=19440302; DOI=10.1371/journal.pone.0005584;
RA Vuilleumier S., Chistoserdova L., Lee M.-C., Bringel F., Lajus A., Zhou Y.,
RA Gourion B., Barbe V., Chang J., Cruveiller S., Dossat C., Gillett W.,
RA Gruffaz C., Haugen E., Hourcade E., Levy R., Mangenot S., Muller E.,
RA Nadalig T., Pagni M., Penny C., Peyraud R., Robinson D.G., Roche D.,
RA Rouy Z., Saenampechek C., Salvignol G., Vallenet D., Wu Z., Marx C.J.,
RA Vorholt J.A., Olson M.V., Kaul R., Weissenbach J., Medigue C.,
RA Lidstrom M.E.;
RT "Methylobacterium genome sequences: a reference blueprint to investigate
RT microbial metabolism of C1 compounds from natural and industrial sources.";
RL PLoS ONE 4:E5584-E5584(2009).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FP103042; CAX27201.1; -; Genomic_DNA.
DR RefSeq; WP_015824614.1; NC_012988.1.
DR AlphaFoldDB; C7C7S5; -.
DR GeneID; 72992282; -.
DR KEGG; mdi:METDI5597; -.
DR HOGENOM; CLU_000022_69_3_5; -.
DR Proteomes; UP000008070; Chromosome.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF322; POLYKETIDE BETA-KETOACYL SYNTHASE 2-RELATED; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:CAX27201.1};
KW Transferase {ECO:0000313|EMBL:CAX27201.1}.
FT DOMAIN 7..256
FT /note="Beta-ketoacyl synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00109"
SQ SEQUENCE 381 AA; 39093 MW; 8D68AA123C389090 CRC64;
MSRPQARDVV VTGIGLVSCA GEGIETHLNA FASHAPPRTD AETFAPYPVH PVAPVSLDAQ
IPKKSDQRQM EAWQRLGVYA AGLALDSAGV KEDAGFKSAL PLVVAAGGGE RDYAVDGAIL
TGLRGTNDPG AFLNERLLND LRPTLFLAQL SNLLAGNISI VHGVTGASRT FMGEESSGVD
ALRIGHARIA SGQVDTMMVG GSYNAERPDV MVVHEMGGYL LKTAYRPVFE RGAEGTGGFV
LGSAAAFLVL EAAEHAAARG ARALARLMPV ANDRVARTPG SVSASLTRLI GEAGIERPDV
VLSGATGLAD LAAEEIAGLD AALPGARIRA TGDMIGHPME VAAPFGAALA AALCAAGSAA
EVAVTSVGHR RGEGVIRVVR I
//
