ID   C7CBQ1_METED            Unreviewed;       447 AA.
AC   C7CBQ1;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 77.
DE   SubName: Full=Sulfite oxidase {ECO:0000313|EMBL:CAX22422.1};
DE            EC=1.8.3.1 {ECO:0000313|EMBL:CAX22422.1};
GN   Name=soxC {ECO:0000313|EMBL:CAX22422.1};
GN   ORFNames=METD_I0786 {ECO:0000313|EMBL:CAX22422.1};
OS   Methylorubrum extorquens (strain DSM 6343 / CIP 106787 / DM4)
OS   (Methylobacterium extorquens).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Methylobacteriaceae; Methylorubrum.
OX   NCBI_TaxID=661410 {ECO:0000313|EMBL:CAX22422.1, ECO:0000313|Proteomes:UP000008070};
RN   [1] {ECO:0000313|Proteomes:UP000008070}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 6343 / CIP 106787 / DM4
RC   {ECO:0000313|Proteomes:UP000008070};
RX   PubMed=19440302; DOI=10.1371/journal.pone.0005584;
RA   Vuilleumier S., Chistoserdova L., Lee M.-C., Bringel F., Lajus A., Zhou Y.,
RA   Gourion B., Barbe V., Chang J., Cruveiller S., Dossat C., Gillett W.,
RA   Gruffaz C., Haugen E., Hourcade E., Levy R., Mangenot S., Muller E.,
RA   Nadalig T., Pagni M., Penny C., Peyraud R., Robinson D.G., Roche D.,
RA   Rouy Z., Saenampechek C., Salvignol G., Vallenet D., Wu Z., Marx C.J.,
RA   Vorholt J.A., Olson M.V., Kaul R., Weissenbach J., Medigue C.,
RA   Lidstrom M.E.;
RT   "Methylobacterium genome sequences: a reference blueprint to investigate
RT   microbial metabolism of C1 compounds from natural and industrial sources.";
RL   PLoS ONE 4:E5584-E5584(2009).
CC   -!- COFACTOR:
CC       Name=Mo-molybdopterin; Xref=ChEBI:CHEBI:71302;
CC         Evidence={ECO:0000256|ARBA:ARBA00001924};
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DR   EMBL; FP103042; CAX22422.1; -; Genomic_DNA.
DR   AlphaFoldDB; C7CBQ1; -.
DR   KEGG; mdi:METDI0786; -.
DR   HOGENOM; CLU_003827_5_5_5; -.
DR   Proteomes; UP000008070; Chromosome.
DR   GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR   GO; GO:0008482; F:sulfite oxidase activity; IEA:UniProtKB-EC.
DR   Gene3D; 2.60.40.650; -; 1.
DR   Gene3D; 3.90.420.10; Oxidoreductase, molybdopterin-binding domain; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR005066; MoCF_OxRdtse_dimer.
DR   InterPro; IPR008335; Mopterin_OxRdtase_euk.
DR   InterPro; IPR000572; OxRdtase_Mopterin-bd_dom.
DR   InterPro; IPR036374; OxRdtase_Mopterin-bd_sf.
DR   InterPro; IPR030835; Sulfite_DH_SoxC.
DR   InterPro; IPR006311; TAT_signal.
DR   NCBIfam; TIGR04555; sulfite_DH_soxC; 1.
DR   PANTHER; PTHR19372:SF7; SULFITE OXIDASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR19372; SULFITE REDUCTASE; 1.
DR   Pfam; PF03404; Mo-co_dimer; 1.
DR   Pfam; PF00174; Oxidored_molyb; 1.
DR   PRINTS; PR00407; EUMOPTERIN.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   SUPFAM; SSF56524; Oxidoreductase molybdopterin-binding domain; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:CAX22422.1}.
FT   DOMAIN          137..297
FT                   /note="Oxidoreductase molybdopterin-binding"
FT                   /evidence="ECO:0000259|Pfam:PF00174"
FT   DOMAIN          318..431
FT                   /note="Moybdenum cofactor oxidoreductase dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03404"
FT   REGION          1..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..23
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   447 AA;  48907 MW;  0F891F67EFC6D199 CRC64;
     MASPPRTPRD PRERQEDSMS DDDGMNAVTR APRSRRQILA AGSALVGGSL AGGVATPARA
     EPGSGLDNTP PNVPRWMKKP GADVGSQLYG TPSEFEKGVI RNVPKNGKQY TSSASRTPLQ
     DLDGIITPNG LFYERHHGGI PAIDPAQHRL MIHGLVERPL LLTMDELRRF PTESRIYFLE
     CSGNPGFEAI KQARTASDLV GLASCCEWTG VRLKTVLDEV GVTPEARWVV AEGADAAALT
     RSVPLEKCLD DALLVFSQNG ERLRPQQGYP LRLLLPGFEG NMSVKWLRRL NVVAEPAYSR
     EETAKYTDSM PDGTARQFTF TMEAKSIITR PSGTHRIAGG FNEITGLAWS GRGRITGVEV
     SVDGGGTWHP AGLQEPVLSR AFTRFRYPWT WDGRPTTILS RATDETGYVQ PSFDDLTTVR
     GMKSFYHNNA VVPWRIAADG KVSNGYV
//