ID C7CLY6_METED Unreviewed; 268 AA.
AC C7CLY6;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=rRNA methylase {ECO:0000313|EMBL:CAX21739.1};
DE EC=2.1.1.34 {ECO:0000313|EMBL:CAX21739.1};
GN Name=rrm1 {ECO:0000313|EMBL:CAX21739.1};
GN ORFNames=METD_I0062 {ECO:0000313|EMBL:CAX21739.1};
OS Methylorubrum extorquens (strain DSM 6343 / CIP 106787 / DM4)
OS (Methylobacterium extorquens).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylorubrum.
OX NCBI_TaxID=661410 {ECO:0000313|EMBL:CAX21739.1, ECO:0000313|Proteomes:UP000008070};
RN [1] {ECO:0000313|Proteomes:UP000008070}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6343 / CIP 106787 / DM4
RC {ECO:0000313|Proteomes:UP000008070};
RX PubMed=19440302; DOI=10.1371/journal.pone.0005584;
RA Vuilleumier S., Chistoserdova L., Lee M.-C., Bringel F., Lajus A., Zhou Y.,
RA Gourion B., Barbe V., Chang J., Cruveiller S., Dossat C., Gillett W.,
RA Gruffaz C., Haugen E., Hourcade E., Levy R., Mangenot S., Muller E.,
RA Nadalig T., Pagni M., Penny C., Peyraud R., Robinson D.G., Roche D.,
RA Rouy Z., Saenampechek C., Salvignol G., Vallenet D., Wu Z., Marx C.J.,
RA Vorholt J.A., Olson M.V., Kaul R., Weissenbach J., Medigue C.,
RA Lidstrom M.E.;
RT "Methylobacterium genome sequences: a reference blueprint to investigate
RT microbial metabolism of C1 compounds from natural and industrial sources.";
RL PLoS ONE 4:E5584-E5584(2009).
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DR EMBL; FP103042; CAX21739.1; -; Genomic_DNA.
DR RefSeq; WP_012751964.1; NC_012988.1.
DR AlphaFoldDB; C7CLY6; -.
DR GeneID; 72987456; -.
DR KEGG; mdi:METDI0062; -.
DR HOGENOM; CLU_021322_0_2_5; -.
DR Proteomes; UP000008070; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0141100; F:tRNA (guanine(18)-2'-O)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd18103; SpoU-like_RlmB; 1.
DR Gene3D; 3.30.1330.30; -; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR013123; SpoU_subst-bd.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR NCBIfam; TIGR00186; rRNA_methyl_3; 1.
DR PANTHER; PTHR46429; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR PANTHER; PTHR46429:SF1; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR Pfam; PF08032; SpoU_sub_bind; 1.
DR SMART; SM00967; SpoU_sub_bind; 1.
DR SUPFAM; SSF75217; alpha/beta knot; 1.
DR SUPFAM; SSF55315; L30e-like; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:CAX21739.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CAX21739.1}.
FT DOMAIN 35..108
FT /note="RNA 2-O ribose methyltransferase substrate binding"
FT /evidence="ECO:0000259|SMART:SM00967"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 268 AA; 28177 MW; 7478069698BB8B7E CRC64;
MTPPRDRPAK PYGFRPRPRT QPPGPAAREG RDHVVLYGWH PVSQALANAG RHFHRLLATE
NALARLKEAG IELPIEPEMV RPSAIDRLLG PDAVHQGLYA EAEPLAAPAL DAMPDDALLL
ALDQITDPHN VGAIVRTAAA FGVTAIVTTA RHSPNATGVL AKSASGGLEH VPLVIVRNLA
EALITLGERG FTRIGLDSDA GTTLDAVGPR RPAVLVLGAE GKGLRQRTTE CCDLLVRIDA
TGAIRSLNVS NAAAITLYAL TRSAGTAA
//
