ID C7E5W3_9CALI Unreviewed; 90 AA.
AC C7E5W3;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 08-NOV-2023, entry version 40.
DE SubName: Full=RNA-dependent RNA polymerase {ECO:0000313|EMBL:ACT64668.1};
DE Flags: Fragment;
OS Norovirus Hu/Afyon/22/2007/TR.
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
OX NCBI_TaxID=659261 {ECO:0000313|EMBL:ACT64668.1};
RN [1] {ECO:0000313|EMBL:ACT64668.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Hu/Afyon/22/2007/TR {ECO:0000313|EMBL:ACT64668.1};
RX PubMed=19544225; DOI=10.1080/00365540903071342;
RA Altindis M., Banyai K., Kalayci R., Gulamber C., Koken R., Yoldas Y.,
RA Aykurt P., Martella V.;
RT "Frequency of norovirus in stool samples from hospitalized children due to
RT acute gastroenteritis in Anatolia, Turkey, 2006-2007.";
RL Scand. J. Infect. Dis. 0:1-4(2009).
CC -!- FUNCTION: Viral genome-linked protein is covalently linked to the 5'-
CC end of the positive-strand, negative-strand genomic RNAs and subgenomic
CC RNA. Acts as a genome-linked replication primer. May recruit ribosome
CC to viral RNA thereby promoting viral proteins translation.
CC {ECO:0000256|ARBA:ARBA00025359}.
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DR EMBL; GQ253110; ACT64668.1; -; Genomic_RNA.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001205; RNA-dir_pol_C.
DR InterPro; IPR007094; RNA-dir_pol_PSvirus.
DR Pfam; PF00680; RdRP_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50507; RDRP_SSRNA_POS; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000313|EMBL:ACT64668.1}; Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT DOMAIN 1..90
FT /note="RdRp catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50507"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACT64668.1"
FT NON_TER 90
FT /evidence="ECO:0000313|EMBL:ACT64668.1"
SQ SEQUENCE 90 AA; 9640 MW; 079852F32201FDA9 CRC64;
AMEVMVRFSA EPELAQVVAE DLLAPSQLDV GDFVISVQEG LPSGVPCTSQ WNSIAHWILT
LSAMAEVSGL SPDVVQAHSC FSFYGDDEIV
//
