ID   C7GHU2_9FIRM            Unreviewed;       568 AA.
AC   C7GHU2;
DT   13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT   13-OCT-2009, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=N-6 DNA Methylase {ECO:0000313|EMBL:EEU98612.1};
DE   Flags: Fragment;
GN   ORFNames=ROSINTL182_09513 {ECO:0000313|EMBL:EEU98612.1};
OS   Roseburia intestinalis L1-82.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=536231 {ECO:0000313|EMBL:EEU98612.1, ECO:0000313|Proteomes:UP000004828};
RN   [1] {ECO:0000313|EMBL:EEU98612.1, ECO:0000313|Proteomes:UP000004828}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L1-82 {ECO:0000313|EMBL:EEU98612.1,
RC   ECO:0000313|Proteomes:UP000004828};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA   Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA   Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA   Mardis E.R., Wilson R.K.;
RL   Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEU98612.1}.
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DR   EMBL; ABYJ02000314; EEU98612.1; -; Genomic_DNA.
DR   AlphaFoldDB; C7GHU2; -.
DR   HOGENOM; CLU_480257_0_0_9; -.
DR   Proteomes; UP000004828; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR003356; DNA_methylase_A-5.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR41313; ADENINE-SPECIFIC METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR41313:SF1; DNA METHYLASE ADENINE-SPECIFIC DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02384; N6_Mtase; 1.
DR   PRINTS; PR00507; N12N6MTFRASE.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:EEU98612.1};
KW   Transferase {ECO:0000313|EMBL:EEU98612.1}.
FT   DOMAIN          332..528
FT                   /note="DNA methylase adenine-specific"
FT                   /evidence="ECO:0000259|Pfam:PF02384"
FT   REGION          202..246
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EEU98612.1"
FT   NON_TER         568
FT                   /evidence="ECO:0000313|EMBL:EEU98612.1"
SQ   SEQUENCE   568 AA;  64384 MW;  EBB8BD079A9CDDCF CRC64;
     DEPDSYAVNR KAAELRYIKP IDYADRVAAM DEDLRDAIEI LVSECSCYTP FRAFLMDVVQ
     SDFAFMPNKL ELICEIAMGN VQGERKAYCN NQYGLTEYTL SSADVKVSYK NRNGERAGDT
     VSWREVYEIL SYMVKQPFYC GEDQKAIYQT IKNKIDREKM NPVYRKFFDI EDSVRESRLK
     TRERAIAYGL NTKIDTDGRI ISDEDKNVSA DIPQKDTEPQ EAAPETPAQE VLPPVEGLRG
     KEKTQDQTKL NFHYNLWETE KGGAKTRYQW NIDAICTLKQ IEAENRLATQ EEQTVLSKFV
     GWGGLSQAFD ENNAAWSKEY AELKELLSDE EYSAARATVN NAFYTSPEIA TCINSALVQF
     GFKGGNVLEP SMGIGNFFGS MPAPMQQSRL YGVELDSISG RIAKQLYQNA NISITGFENT
     TYPDNFFDVV MGNVPFGDYK IFDPKYNKYN FRIHDYFLAK ALDQARPGGM VAVITTKGTL
     DKSNPTIRKY LAERAELVGA IRLPNTAFKD NAGTEVTADI LFLQKRERKI DIEPDWVHLG
     VTGDGIAVNS YFAEHPEMML GTMQYDTR
//