ID C7LHT4_BRUMC Unreviewed; 426 AA.
AC C7LHT4;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Uracil-xanthine permease {ECO:0000313|EMBL:ACU49572.1};
GN OrderedLocusNames=BMI_II439 {ECO:0000313|EMBL:ACU49572.1};
OS Brucella microti (strain CCM 4915).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=568815 {ECO:0000313|EMBL:ACU49572.1, ECO:0000313|Proteomes:UP000002188};
RN [1] {ECO:0000313|EMBL:ACU49572.1, ECO:0000313|Proteomes:UP000002188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCM 4915 {ECO:0000313|EMBL:ACU49572.1,
RC ECO:0000313|Proteomes:UP000002188};
RX PubMed=19653890; DOI=10.1186/1471-2164-10-352;
RA Audic S., Lescot M., Claverie J.-M., Scholz H.C.;
RT "Brucella microti: the genome sequence of an emerging pathogen.";
RL BMC Genomics 10:352-352(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; CP001579; ACU49572.1; -; Genomic_DNA.
DR RefSeq; WP_004681807.1; NC_013118.1.
DR AlphaFoldDB; C7LHT4; -.
DR GeneID; 29595796; -.
DR KEGG; bmr:BMI_II439; -.
DR HOGENOM; CLU_017959_1_1_5; -.
DR Proteomes; UP000002188; Chromosome 2.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR PANTHER; PTHR11119:SF3; LD30822P; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 54..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 426 AA; 43679 MW; B7EF7EE110CFD416 CRC64;
MGYFPSWRLT SNAVVLPDER LPAAAAVPMG IQHLLAMSGS TIVAPLLMGF DPNVAVFFSG
IGTLLFFLIT AGRVPSYLGS SFAFIAVVIA ATGYSGSGPN PNIAIALGGI IACGALYSLI
GLIVMFLGTG WVEKLMPPAV TGAIGVSIGL NLAPVAIGQL KGTGAHTSIA LLTVLCMAMI
SAYGPRGTRR LSVLFALLFG YLLVLIAGNG LGIVPGIDFT AVKNAAWFGL PHFTTPAFNW
QAVTLIAPVA IVLVAENLGH IKALGSITGR NMDGYIGRGF FSDGLATMIS GAGGGTGVTT
YAENIGVMAM TKVYSTLIFV IAAIMALILG MSPKFGAILQ TIPAPVLAGL AVSVFGLIAS
AMARIWIVNK VDFADSRNLF TVGVALIFGA GDFTLNIGNF ALGGIATSTL AALVLYQLLG
IGRSDS
//
