ID C7M450_CAPOD Unreviewed; 515 AA.
AC C7M450;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Exo-alpha-sialidase {ECO:0000313|EMBL:ACU91582.1};
DE EC=3.2.1.18 {ECO:0000313|EMBL:ACU91582.1};
GN OrderedLocusNames=Coch_0016 {ECO:0000313|EMBL:ACU91582.1};
OS Capnocytophaga ochracea (strain ATCC 27872 / DSM 7271 / JCM 12966 / NCTC
OS 12371 / VPI 2845) (Bacteroides ochraceus).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Capnocytophaga.
OX NCBI_TaxID=521097 {ECO:0000313|EMBL:ACU91582.1, ECO:0000313|Proteomes:UP000006650};
RN [1] {ECO:0000313|EMBL:ACU91582.1, ECO:0000313|Proteomes:UP000006650}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27872 / DSM 7271 / JCM 12966 / VPI 2845
RC {ECO:0000313|Proteomes:UP000006650};
RX PubMed=21304645; DOI=10.4056/sigs.15195;
RA Mavrommatis K., Gronow S., Saunders E., Land M., Lapidus A., Copeland A.,
RA Glavina Del Rio T., Nolan M., Lucas S., Chen F., Tice H., Cheng J.F.,
RA Bruce D., Goodwin L., Pitluck S., Pati A., Ivanova N., Chen A.,
RA Palaniappan K., Chain P., Hauser L., Chang Y.J., Jeffries C.D., Brettin T.,
RA Detter J.C., Han C., Bristow J., Goker M., Rohde M., Eisen J.A.,
RA Markowitz V., Kyrpides N.C., Klenk H.P., Hugenholtz P.;
RT "Complete genome sequence of Capnocytophaga ochracea type strain (VPI
RT 2845).";
RL Stand. Genomic Sci. 1:101-109(2009).
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DR EMBL; CP001632; ACU91582.1; -; Genomic_DNA.
DR RefSeq; WP_012796827.1; NC_013162.1.
DR AlphaFoldDB; C7M450; -.
DR STRING; 521097.Coch_0016; -.
DR CAZy; GH33; Glycoside Hydrolase Family 33.
DR GeneID; 29675474; -.
DR KEGG; coc:Coch_0016; -.
DR eggNOG; COG4409; Bacteria.
DR HOGENOM; CLU_024620_0_0_10; -.
DR Proteomes; UP000006650; Chromosome.
DR GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR InterPro; IPR008377; Sialidase_trypan.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF19; SIALIDASE; 1.
DR Pfam; PF13088; BNR_2; 1.
DR PRINTS; PR01803; TCSIALIDASE.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000313|EMBL:ACU91582.1};
KW Hydrolase {ECO:0000313|EMBL:ACU91582.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006650};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..515
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002979807"
FT DOMAIN 195..490
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13088"
SQ SEQUENCE 515 AA; 57870 MW; F561AB1CFC84532D CRC64;
MKQLFTIIAL CFLSFGYAQK GMTFTQTQMP LATDKDNLIT SFVLPIKQGT EVKELSLQFK
SKKLNLSELS VYVGANAKRE QATLFAKTSN LGCNTKLQGN FKATNDTLFV WISARTTQKP
DLLQKLYLSK VKLITNEAKI TLSNAKKEGQ RFAIALRQRK QDGIECYRIP GLVTTNKGTL
IAVYDNRYNN CKDLQEDIDV GMSRSTDGGQ TWEPMKKVID MGEWGGKTNR LNGVGDPAVL
VDEQTNTIWV MGLWQHGLDP QTMSWWGSKS GMTPEETGQI VVVKSEDDGK TWSEPINITS
QIKNPEWRLF FQGPGRGISM SNGTLVFAGQ FKDKDQVPHS TIIYSKDHGK TWHVGTGAKT
HTTESQVVEL SDGTLMLNMR DDRNRSNYEL SDNYHGRSVA VTADMGKTWV EHNTSRTALT
EPNCMASIIS YKDKKGKQYL FFSNPNDAKD RVNMTIKTSK DEGNTWDKLA SVLLYEQAAM
GYSCLTVIDN KYIGILYEGD GDLYFQKVPI KEFIK
//
