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Database: UniProt
Entry: C7MRN3_SACVD
LinkDB: C7MRN3_SACVD
Original site: C7MRN3_SACVD 
ID   C7MRN3_SACVD            Unreviewed;       597 AA.
AC   C7MRN3;
DT   13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT   13-OCT-2009, sequence version 1.
DT   25-OCT-2017, entry version 67.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Svir_00010 {ECO:0000313|EMBL:ACU95095.1};
OS   Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 /
OS   NBRC 12207 / P101).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Saccharomonospora.
OX   NCBI_TaxID=471857 {ECO:0000313|EMBL:ACU95095.1, ECO:0000313|Proteomes:UP000000841};
RN   [1] {ECO:0000313|EMBL:ACU95095.1, ECO:0000313|Proteomes:UP000000841}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101
RC   {ECO:0000313|Proteomes:UP000000841};
RX   PubMed=21304650; DOI=10.4056/sigs.20263;
RA   Pati A., Sikorski J., Nolan M., Lapidus A., Copeland A.,
RA   Glavina Del Rio T., Lucas S., Chen F., Tice H., Pitluck S.,
RA   Cheng J.F., Chertkov O., Brettin T., Han C., Detter J.C., Kuske C.,
RA   Bruce D., Goodwin L., Chain P., D'haeseleer P., Chen A.,
RA   Palaniappan K., Ivanova N., Mavromatis K., Mikhailova N., Rohde M.,
RA   Tindall B.J., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Saccharomonospora viridis type strain
RT   (P101).";
RL   Stand. Genomic Sci. 1:141-149(2009).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP001683; ACU95095.1; -; Genomic_DNA.
DR   RefSeq; WP_012795528.1; NC_013159.1.
DR   ProteinModelPortal; C7MRN3; -.
DR   STRING; 471857.Svir_00010; -.
DR   EnsemblBacteria; ACU95095; ACU95095; Svir_00010.
DR   KEGG; svi:Svir_00010; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; ATHIERN; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000000841; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000841};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000841}.
FT   DOMAIN      288    416       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      501    570       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     296    303       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   597 AA;  65745 MW;  7C094B7E1511A94F CRC64;
     MSEHQLNLAV VWEQVVAELS EGTLSPQQRA WMRVTRPIGL LDGTALLAAP SDFAKEAIER
     ALREPITSAL SRHLGREVSL AVKVDSTEST PPPPPSPLPT GPGSPGDAAM PPSATTLHSP
     PSPSTPPTHA RYGPPLGGHP ERPPVPSNDD TIIIPAVRPP RADHTEARIP GAHRSPSSAM
     PSTHPPSRPA GPPQPPSNLP SRPKPSAEGE DGDDEVDEEG EALAAVHEIW PTFSGQPIAG
     QPYTAPAQPQ TSKTRLNEKY TFDTFVIGAS NRFAHAAAVA VAEAPSRAYN PLFVWGESGL
     GKTHLLHAVG HYAQRLFPGM RVRYVSTEEF TNDFINSLRD DRKVAFQRRY RDIDILLVDD
     IQFLEGKEGT QEEFFHTFNT LHNANKQIVV SSDRPPKRLE TLEERLRTRF EWGLITDIQP
     PELETRIAIL RKKAAQDRLA VPGEVLEFIA ARVEANIREL EGALIRVTAF ASLNQQPVDV
     GLAEVVLRDL MPTDSQAPEI SASMIMNVTA EFFDVTVEDL CGPGKTKALA TARQIAMYLC
     RELTDMSLPR IGQTFGGRDH TTVMHADKKI RKEMAERRRI YDQVQELTSR IKQYARQ
//
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