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Database: UniProt
Entry: C7N0K0_SLAHD
LinkDB: C7N0K0_SLAHD
Original site: C7N0K0_SLAHD 
ID   C7N0K0_SLAHD            Unreviewed;       501 AA.
AC   C7N0K0;
DT   13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT   13-OCT-2009, sequence version 1.
DT   05-JUL-2017, entry version 63.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Shel_00010 {ECO:0000313|EMBL:ACV21078.1};
OS   Slackia heliotrinireducens (strain ATCC 29202 / DSM 20476 / NCTC 11029
OS   / RHS 1) (Peptococcus heliotrinreducens).
OC   Bacteria; Actinobacteria; Coriobacteriia; Eggerthellales;
OC   Eggerthellaceae; Slackia.
OX   NCBI_TaxID=471855 {ECO:0000313|EMBL:ACV21078.1, ECO:0000313|Proteomes:UP000002026};
RN   [1] {ECO:0000313|EMBL:ACV21078.1, ECO:0000313|Proteomes:UP000002026}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29202 / DSM 20476 / NCTC 11029 / RHS 1
RC   {ECO:0000313|Proteomes:UP000002026};
RX   PubMed=21304663; DOI=10.4056/sigs.37633;
RA   Pukall R., Lapidus A., Nolan M., Copeland A., Glavina Del Rio T.,
RA   Lucas S., Chen F., Tice H., Cheng J.F., Chertkov O., Bruce D.,
RA   Goodwin L., Kuske C., Brettin T., Detter J.C., Han C., Pitluck S.,
RA   Pati A., Mavrommatis K., Ivanova N., Ovchinnikova G., Chen A.,
RA   Palaniappan K., Schneider S., Rohde M., Chain P., D'haeseleer P.,
RA   Goker M., Bristow J., Eisen J.A., Markowitz V., Kyrpides N.C.,
RA   Klenk H.P., Hugenholtz P.;
RT   "Complete genome sequence of Slackia heliotrinireducens type strain
RT   (RHS 1).";
RL   Stand. Genomic Sci. 1:234-241(2009).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP001684; ACV21078.1; -; Genomic_DNA.
DR   RefSeq; WP_012797189.1; NC_013165.1.
DR   ProteinModelPortal; C7N0K0; -.
DR   STRING; 471855.Shel_00010; -.
DR   EnsemblBacteria; ACV21078; ACV21078; Shel_00010.
DR   KEGG; shi:Shel_00010; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000002026; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002026};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002026}.
FT   DOMAIN      184    307       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      408    477       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     192    199       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   501 AA;  56444 MW;  8F52A19AFDA1E8D2 CRC64;
     MDITDLYATW NSVCNQIKTY GDVNPHQVDA YFSRLHPQAI SEGFLVLTAD TAFFKMQVEK
     RYLTHIIQAL KDTTGIDFMV EIEVDETEPA PQPVVVQQPV FEPQQDVGLF PGQPISTQLV
     TETEPQPSCL TGEGSEAMME EEIARSKAAT LASSLTFESF VTGNSNMLAY SLAVAVAEAP
     GQPNTNPLFI YGKSGLGKTH LLRAIQNYVM ETNPTMDVVY IDSSEFLAEY TSAVTAHERD
     RKSFQNFQNR FLDADMLLID DVQFFQGKSA TLDIVFQLFN HLVDAGKQVV LSADRAPKMI
     DIDERYKSRF NQGATVNVDP PELEVKLGII KNFINEYEAT SESGPLNIPD DIQIYIAEIS
     SSNVRELKSA VTKVIFQIRY SDSGEITLSE VKTLLEDHFS SGITKRLNIG MIQHEVEQYY
     KVTHAELIGV KRSRNIVFAR QVAIYLCRNM LDIPYAAIGK KFGQRDHSTI MHSVKLIEDR
     MRSSREMQEE IEIITKMIRE S
//
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