ID C7NAZ0_LEPBD Unreviewed; 333 AA.
AC C7NAZ0;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Isocitrate dehydrogenase (NAD(+)) {ECO:0000313|EMBL:ACV39321.1};
DE EC=1.1.1.41 {ECO:0000313|EMBL:ACV39321.1};
GN OrderedLocusNames=Lebu_1446 {ECO:0000313|EMBL:ACV39321.1};
OS Leptotrichia buccalis (strain ATCC 14201 / DSM 1135 / JCM 12969 / NCTC
OS 10249 / C-1013-b).
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Leptotrichiaceae;
OC Leptotrichia.
OX NCBI_TaxID=523794 {ECO:0000313|EMBL:ACV39321.1, ECO:0000313|Proteomes:UP000001910};
RN [1] {ECO:0000313|EMBL:ACV39321.1, ECO:0000313|Proteomes:UP000001910}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14201 / DSM 1135 / JCM 12969 / NCTC 10249 / C-1013-b
RC {ECO:0000313|Proteomes:UP000001910};
RX PubMed=21304648; DOI=10.4056/sigs.1854;
RA Ivanova N., Gronow S., Lapidus A., Copeland A., Glavina Del Rio T.,
RA Nolan M., Lucas S., Chen F., Tice H., Cheng J.F., Saunders E., Bruce D.,
RA Goodwin L., Brettin T., Detter J.C., Han C., Pitluck S., Mikhailova N.,
RA Pati A., Mavrommatis K., Chen A., Palaniappan K., Land M., Hauser L.,
RA Chang Y.J., Jeffries C.D., Chain P., Rohde C., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Leptotrichia buccalis type strain (C-1013-
RT b).";
RL Stand. Genomic Sci. 1:126-132(2009).
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
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DR EMBL; CP001685; ACV39321.1; -; Genomic_DNA.
DR RefSeq; WP_015769662.1; NC_013192.1.
DR AlphaFoldDB; C7NAZ0; -.
DR STRING; 523794.Lebu_1446; -.
DR KEGG; lba:Lebu_1446; -.
DR eggNOG; COG0473; Bacteria.
DR HOGENOM; CLU_031953_0_1_0; -.
DR OrthoDB; 9806254at2; -.
DR Proteomes; UP000001910; Chromosome.
DR GO; GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR PANTHER; PTHR11835:SF34; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR PROSITE; PS00470; IDH_IMDH; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:ACV39321.1}.
FT DOMAIN 3..328
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 333 AA; 36872 MW; 8F6457DE9C496F1E CRC64;
MKKVTLIPGD GIGYEISESL VEIFKAAKVP VEFETENAGT DVYEKTGELI PESLYESVEK
NKIAIKGPIT TPIGKGFRSI NVYLRKKYDL YTNFRPSRNL PGIETRYKNI ELAIFRENTE
GIYIGEEKFE DEEKTSAIAI KRITRKGSER IIKSAFEYAK NNKISKVTVV HKANILKYTD
GMFLEIAREV AKNYEGIDLE ELIIDNMCMQ LVTNPERFKV IVTMNLYGDI LSDLVAGLVG
GLGVAPGANI GDDIAIFEAV HGSAPDIAGQ NKANPLALLL SSLEMLKYLN LNDFAQKIEN
AILKTLESDC KTGDLGGNAT TTEFTKKIIE NLG
//
