ID C7NRJ0_HALUD Unreviewed; 851 AA.
AC C7NRJ0;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Heavy metal translocating P-type ATPase {ECO:0000313|EMBL:ACV11926.1};
GN OrderedLocusNames=Huta_1754 {ECO:0000313|EMBL:ACV11926.1};
OS Halorhabdus utahensis (strain DSM 12940 / JCM 11049 / AX-2).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Halorhabdus.
OX NCBI_TaxID=519442 {ECO:0000313|EMBL:ACV11926.1, ECO:0000313|Proteomes:UP000002071};
RN [1] {ECO:0000313|EMBL:ACV11926.1, ECO:0000313|Proteomes:UP000002071}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12940 / JCM 11049 / AX-2
RC {ECO:0000313|Proteomes:UP000002071};
RX PubMed=21304660; DOI=10.4056/sigs.31864;
RA Anderson I., Tindall B.J., Pomrenke H., Goker M., Lapidus A., Nolan M.,
RA Copeland A., Glavina Del Rio T., Chen F., Tice H., Cheng J.F., Lucas S.,
RA Chertkov O., Bruce D., Brettin T., Detter J.C., Han C., Goodwin L.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.D., Pitluck S., Pati A.,
RA Mavromatis K., Ivanova N., Ovchinnikova G., Chen A., Palaniappan K.,
RA Chain P., Rohde M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Halorhabdus utahensis type strain (AX-2).";
RL Stand. Genomic Sci. 1:218-225(2009).
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DR EMBL; CP001687; ACV11926.1; -; Genomic_DNA.
DR AlphaFoldDB; C7NRJ0; -.
DR STRING; 519442.Huta_1754; -.
DR KEGG; hut:Huta_1754; -.
DR eggNOG; arCOG02763; Archaea.
DR eggNOG; arCOG02764; Archaea.
DR HOGENOM; CLU_001771_0_3_2; -.
DR Proteomes; UP000002071; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00371; HMA; 2.
DR CDD; cd02094; P-type_ATPase_Cu-like; 1.
DR Gene3D; 3.30.70.100; -; 2.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR006121; HMA_dom.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR027256; P-typ_ATPase_IB.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01525; ATPase-IB_hvy; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR43520; ATP7, ISOFORM B; 1.
DR PANTHER; PTHR43520:SF8; COPPER-TRANSPORTING ATPASE 2; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00403; HMA; 2.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00943; CUATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 2.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
DR PROSITE; PS50846; HMA_2; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002071};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 155..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 815..835
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..58
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
FT DOMAIN 60..126
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
SQ SEQUENCE 851 AA; 89611 MW; 65A26D6C3628B8C5 CRC64;
MSCANCSGTI QDTLESLDGV IEASANFATD EGSVEYDPEV VTLGEIYEAV ENAGYGAVSE
TVTVAISDMS CANCAEANAT ALEDTPGVIG AEVNYATDEA QVTYNPAEAS RADLYDAIEA
AGYSPVREDD DDAGDAGADA RDAARDEEIR KQLRLTLFGA LLSAPMLVFM ADKLVLGGGI
VAGVESLVGI RLGWVEFALA TPVQALLGWP FYKNSYNALV NNRRANMDVL IALGSSTAYL
YSVAVLSGLI AGEVYFDTAA LILVFITLGN YLEARSKGQA GEALRKLLEM EAETATLIGP
DGTEREVPLE DVQTGDLMKV RPGEQIPTDG VVVDGQSAVD ESMVTGESVP VEKREGDEVV
GSTINENGLL TVKATKVGAD TALQQIVQTV KEAQSRQPEI QNLADRISAY FVPAVIANAV
FWGVVWFAFP EVLAGFVDAL PLWGLVAGGP EIVGGAVSIF EFAVIVFASA VLIACPCALG
LATPAATMVG TTIGAQHGVL FKGGDILERA RDVDTVVFDK TGTLTEGEME LTDVVALDGE
ETAADGGAVA ERQRHTEDDV LRLAAAAESG SEHPLARAIV DGAEERGLEI PEPDDFENVP
GHGIRATIDG SEVLVGNRKL LEDEGIDPAP AEETMERLER EGKTAMLVAI DGELAGVVAD
ADTVKEGAKE AVAALRERGV EVMMITGDNE RTARAVAEQV GIDPDNVRAE VLPEDKSDAV
EQIQSDGRKA MMVGDGVNDA PALAVAHVGT AIGSGTDVAI EAADVTLMRS DPQDVVKAIR
ISDATLQKIK QNLLWALGYN TAMIPLASLG LLQPVLAAAA MAFSSVSVLT NSLLFRRYTP
EEDYRIFGRL R
//
