ID C7NX31_HALMD Unreviewed; 1066 AA.
AC C7NX31;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Methyl-accepting chemotaxis sensory transducer {ECO:0000313|EMBL:ACV46396.1};
GN OrderedLocusNames=Hmuk_0259 {ECO:0000313|EMBL:ACV46396.1};
OS Halomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB
OS 13541) (Haloarcula mukohataei).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Halomicrobium.
OX NCBI_TaxID=485914 {ECO:0000313|EMBL:ACV46396.1, ECO:0000313|Proteomes:UP000001746};
RN [1] {ECO:0000313|EMBL:ACV46396.1, ECO:0000313|Proteomes:UP000001746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541
RC {ECO:0000313|Proteomes:UP000001746};
RX PubMed=21304667; DOI=10.4056/sigs.42644;
RA Tindall B.J., Schneider S., Lapidus A., Copeland A., Glavina Del Rio T.,
RA Nolan M., Lucas S., Chen F., Tice H., Cheng J.F., Saunders E., Bruce D.,
RA Goodwin L., Pitluck S., Mikhailova N., Pati A., Ivanova N., Mavrommatis K.,
RA Chen A., Palaniappan K., Chain P., Land M., Hauser L., Chang Y.J.,
RA Jeffries C.D., Brettin T., Han C., Rohde M., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.,
RA Detter J.C.;
RT "Complete genome sequence of Halomicrobium mukohataei type strain (arg-
RT 2).";
RL Stand. Genomic Sci. 1:270-277(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; CP001688; ACV46396.1; -; Genomic_DNA.
DR AlphaFoldDB; C7NX31; -.
DR STRING; 485914.Hmuk_0259; -.
DR KEGG; hmu:Hmuk_0259; -.
DR eggNOG; arCOG02320; Archaea.
DR eggNOG; arCOG02342; Archaea.
DR HOGENOM; CLU_288310_0_0_2; -.
DR Proteomes; UP000001746; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd11386; MCP_signal; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 1.20.120.1530; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033462; Cache_3-Cache_2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF17201; Cache_3-Cache_2; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00304; HAMP; 2.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 2.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000001746};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284}; Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 546..599
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 753..989
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT REGION 804..832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1042..1066
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..832
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1066 AA; 115087 MW; E23AEBD6E41FC0FC CRC64;
MSMDLKVKLV VLMLAISLLP LGSVGALATQ NMGSLNQDAQ DRSAQELRGA MTDDLNNSVR
ARQSSLQNQF DQREVDMRSL AQSGAMDNYQ AARQGKMQLV QEASQRQVGY TALEMRNAIE
STTQTVLDTE YDGREWEELS PREQRAVKQR VERIIAGTDG DGTTADGTMD ETFQPGYIGE
TGYAYVTDLD SNVVVHHRLE DGHNFADDSG GSLTVFDDIK ANIESTPALR NGETWGVAEY
EWEDTTQDGN PTETQLVAYT YYEPFDWIVA PSVYYYELQE RAVADSEARL ADSFEQYLET
RTVSVNREQR YAYDEIIFVD KRGREVISAT REGERAVTER DGSGWHADKS WFTSAGAVAN
GEVAFNRIEE ENGSQRMYVS TPVYQDGRFR GVVVAQFNYS IVTEITNGVS VGETGYLYVV
NDRGEMVSHP NETKVAQRVD VAGGEYGEEL GNITTEQMLA ARSGMATHTR TVGGEETTRY
VVYAPLQVGD RQFSLVGTVP ESDIEGPIAA LGDALQQRTD DARNLILLLS GIAALVVVAA
GYAVARYVAS PIEQMRDRAT EMAQGRFDGE LDVDDRDDEI GEMVEAFEEM EANLTRQITE
IEAVSASLSE GEIDDDLHTD LPGSFGDIMT DLQDGMTQLR TSFAQISRAS ENVRTGKLDQ
EIDSDLPGEY GAVMDELDAG LQQLSESFDR LRTASTALSE RRLDEDLGTD LPGAYGDVMT
NIDAGLDAVE ESIARVQSIA REVSSATDDA AASAQEVERA SQEVAESVQE ISHGADRQSE
QLQEAAAEMN DMSATVEEVA SSAVDVANTS ERAADRAEAG SERASEASRE IEGIEAETEQ
AVEQVAALES EIDEISEIVS MITDIAEQTN MLALNASIEA ARAGEAGEGF AVVADEIKGL
AGEAAAATEE IDGLITELQA TTGETVDDIE SMRDRVENGA DTIEDAIAMF DEIAESATEA
EHGVREISEA TDDQAASTEE VVAMVDEVSS VSQQAAAEAT SVSSAAEEQA ASVNNISQNV
RSVADMADDL EALVEAFEVQ QSAADGDASA AGASADGGWS PDDGAE
//
