ID C7NZK1_HALMD Unreviewed; 260 AA.
AC C7NZK1;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=fructose-bisphosphate aldolase {ECO:0000256|ARBA:ARBA00013068};
DE EC=4.1.2.13 {ECO:0000256|ARBA:ARBA00013068};
GN OrderedLocusNames=Hmuk_2663 {ECO:0000313|EMBL:ACV48769.1};
OS Halomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB
OS 13541) (Haloarcula mukohataei).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Halomicrobium.
OX NCBI_TaxID=485914 {ECO:0000313|EMBL:ACV48769.1, ECO:0000313|Proteomes:UP000001746};
RN [1] {ECO:0000313|EMBL:ACV48769.1, ECO:0000313|Proteomes:UP000001746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541
RC {ECO:0000313|Proteomes:UP000001746};
RX PubMed=21304667; DOI=10.4056/sigs.42644;
RA Tindall B.J., Schneider S., Lapidus A., Copeland A., Glavina Del Rio T.,
RA Nolan M., Lucas S., Chen F., Tice H., Cheng J.F., Saunders E., Bruce D.,
RA Goodwin L., Pitluck S., Mikhailova N., Pati A., Ivanova N., Mavrommatis K.,
RA Chen A., Palaniappan K., Chain P., Land M., Hauser L., Chang Y.J.,
RA Jeffries C.D., Brettin T., Han C., Rohde M., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.,
RA Detter J.C.;
RT "Complete genome sequence of Halomicrobium mukohataei type strain (arg-
RT 2).";
RL Stand. Genomic Sci. 1:270-277(2009).
CC -!- SIMILARITY: Belongs to the DeoC/FbaB aldolase family.
CC {ECO:0000256|ARBA:ARBA00008116}.
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DR EMBL; CP001688; ACV48769.1; -; Genomic_DNA.
DR RefSeq; WP_015763611.1; NC_013202.1.
DR AlphaFoldDB; C7NZK1; -.
DR STRING; 485914.Hmuk_2663; -.
DR GeneID; 8412213; -.
DR KEGG; hmu:Hmuk_2663; -.
DR eggNOG; arCOG04044; Archaea.
DR HOGENOM; CLU_057069_2_2_2; -.
DR OrthoDB; 6329at2157; -.
DR Proteomes; UP000001746; Chromosome.
DR GO; GO:0004332; F:fructose-bisphosphate aldolase activity; IEA:UniProtKB-EC.
DR CDD; cd00958; DhnA; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002915; DeoC/FbaB/LacD_aldolase.
DR InterPro; IPR041720; FbaB-like.
DR PANTHER; PTHR47916:SF1; 3-HYDROXY-5-PHOSPHONOOXYPENTANE-2,4-DIONE THIOLASE-RELATED; 1.
DR PANTHER; PTHR47916; FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 1; 1.
DR Pfam; PF01791; DeoC; 1.
DR PIRSF; PIRSF038992; Aldolase_Ia; 1.
DR SMART; SM01133; DeoC; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:ACV48769.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001746}.
FT ACT_SITE 146
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR038992-1"
FT ACT_SITE 177
FT /note="Schiff-base intermediate with dihydroxyacetone-P"
FT /evidence="ECO:0000256|PIRSR:PIRSR038992-1"
SQ SEQUENCE 260 AA; 28190 MW; A59EE95942821A4D CRC64;
MHVSDDSPLV RNGKTIVLAH DHGLEHGPKQ FDGVEARLDP NAVFEMATHD AVTALAVGKG
LTETYYPSYD DEVNLLAKLN GGSDLWMGEP YAAQNWSVDY AAELGADAVG YTVYPGVNDE
PRLFEDFGPV QERARDHDLP IAMWSYPRGQ AIKEHRSRDA IAYAARIGLE LGGDFVKVKY
PRSPGAMAHA VDAAGDTGVL LSGGSKTSDR EFLELVEGCL DAGVSGLAVG RNVWQREDPY
DILDKLERVV FEGASADDVL
//
