ID C7RD65_ANAPD Unreviewed; 344 AA.
AC C7RD65;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Isocitrate dehydrogenase (NAD(+)) {ECO:0000313|EMBL:ACV29128.1};
DE EC=1.1.1.41 {ECO:0000313|EMBL:ACV29128.1};
GN OrderedLocusNames=Apre_1101 {ECO:0000313|EMBL:ACV29128.1};
OS Anaerococcus prevotii (strain ATCC 9321 / DSM 20548 / JCM 6508 / NCTC 11806
OS / PC1) (Peptostreptococcus prevotii) (Peptococcus prevotii).
OC Bacteria; Bacillota; Tissierellia; Tissierellales; Peptoniphilaceae;
OC Anaerococcus.
OX NCBI_TaxID=525919 {ECO:0000313|EMBL:ACV29128.1, ECO:0000313|Proteomes:UP000002294};
RN [1] {ECO:0000313|EMBL:ACV29128.1, ECO:0000313|Proteomes:UP000002294}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 9321 / DSM 20548 / JCM 6508 / NCTC 11806 / PC1
RC {ECO:0000313|Proteomes:UP000002294};
RX PubMed=21304652; DOI=10.4056/sigs.24194;
RA Labutti K., Pukall R., Steenblock K., Glavina Del Rio T., Tice H.,
RA Copeland A., Cheng J.F., Lucas S., Chen F., Nolan M., Bruce D., Goodwin L.,
RA Pitluck S., Ivanova N., Mavromatis K., Ovchinnikova G., Pati A., Chen A.,
RA Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Chain P.,
RA Saunders E., Brettin T., Detter J.C., Han C., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.,
RA Lapidus A.;
RT "Complete genome sequence of Anaerococcus prevotii type strain (PC1).";
RL Stand. Genomic Sci. 1:159-165(2009).
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001708; ACV29128.1; -; Genomic_DNA.
DR AlphaFoldDB; C7RD65; -.
DR STRING; 525919.Apre_1101; -.
DR KEGG; apr:Apre_1101; -.
DR eggNOG; COG0473; Bacteria.
DR HOGENOM; CLU_031953_0_1_9; -.
DR Proteomes; UP000002294; Chromosome.
DR GO; GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR PANTHER; PTHR11835:SF34; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR PROSITE; PS00470; IDH_IMDH; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:ACV29128.1}.
FT DOMAIN 11..335
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 344 AA; 38209 MW; 7F7CBF79F75F2F51 CRC64;
MRKDWNYRSM YVTLIKGDGI GPEITESLKK VVSSLKVDIE FEEINAGLSV FEKEGVYIPQ
TLFDSIKKNK IAIKGPITTP IGHGFRSINV ELRKKFDLYA NIRPIKSPGP LDLKFDGVDM
VIFRENTEDL YAGVEEMVSD NEAHSIKIIT REKSERIIKA AFEYVRANKR EKVSVISKAN
IMKLSDGLFL DVAREIAKEY PDIEFEELLV DNTAMQMVIN PERFDVIVTE NLYGDILSDL
GAGLVGGLGL MPGVNKGKDI AIYESIHGSA PDIAGKNLAN PIALLLSFCL LLDDIGEKDK
AKVLRGAIYE TLKDKKNYTR DLGGTNSTYG ITDTMISFLG DNNG
//
