ID C7SIN3_9ENTR Unreviewed; 393 AA.
AC C7SIN3;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Truncated integrase B {ECO:0000313|EMBL:ACR39091.1};
GN Name=IntB {ECO:0000313|EMBL:ACR39091.1};
OS Enterobacter sp. enrichment culture clone 05-680.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Enterobacter; environmental samples.
OX NCBI_TaxID=645640 {ECO:0000313|EMBL:ACR39091.1};
RN [1] {ECO:0000313|EMBL:ACR39091.1}
RP NUCLEOTIDE SEQUENCE.
RA Paauw A., Leverstein-van Hall M.A., Verhoef J., Fluit A.C.;
RT "Genotypic and functional characterization of the High Pathogenicity Island
RT of an epidemic Enterobacter hormaechei.";
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
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DR EMBL; FJ423206; ACR39091.1; -; Genomic_DNA.
DR AlphaFoldDB; C7SIN3; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR CDD; cd00801; INT_P4_C; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 3.30.160.390; Integrase, DNA-binding domain; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR038488; Integrase_DNA-bd_sf.
DR InterPro; IPR025166; Integrase_DNA_bind_dom.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004107; Integrase_SAM-like_N.
DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR PANTHER; PTHR30629:SF9; PROTEIN INTB-RELATED; 1.
DR Pfam; PF13356; Arm-DNA-bind_3; 1.
DR Pfam; PF14659; Phage_int_SAM_3; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248};
KW Viral genome integration {ECO:0000256|ARBA:ARBA00023195};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 96..176
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 199..393
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
SQ SEQUENCE 393 AA; 44811 MW; 889C4E6BE1A35251 CRC64;
MSLTDAKIRT LKPSDKPFKV FDSHGLYLRV KPGGSRHWYL KYRISGKESR IALGAYPAIS
LSDARQQREG IRKMLALNIN PVQQRAAVRG SRTPEKVFKN VALAWHKSNR KWSQNTADRL
LASLNNHIFP VIGNLPVSEL KPRHFIDLQK GIEEKGLLEV ASRTRQHLSN IIRHAVHQEL
IDTNPAANLG GVTTPPVRRH YPALPLERLP ELLERIGAYH QGRELTRHAV LLMLHVFIRS
SELRFARWSE IDFTNRVWTI PATREPIIGV HYSGRGAKMR MPHIVPLSEQ SIAILKQIKD
ITGNNELIFP GDHNPYKPMC ENTVNKALRV MGYDTKKDIC GHGFRAMACS ALMESGLWAK
DAVERQMSHQ ERNTVRMAYI HKAEHLEARK AMM
//
