ID   C8CHD8_HAEIF            Unreviewed;       344 AA.
AC   C8CHD8;
DT   13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT   13-OCT-2009, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=glycerophosphodiester phosphodiesterase {ECO:0000256|ARBA:ARBA00012247};
DE            EC=3.1.4.46 {ECO:0000256|ARBA:ARBA00012247};
DE   Flags: Fragment;
OS   Haemophilus influenzae.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=727 {ECO:0000313|EMBL:ACV30032.1};
RN   [1] {ECO:0000313|EMBL:ACV30032.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=M06297 {ECO:0000313|EMBL:ACV30032.1};
RX   PubMed=21276750; DOI=10.1016/j.ijmm.2010.11.004;
RA   Wang X., Mair R., Hatcher C., Theodore M.J., Edmond K., Wu H.M.,
RA   Harcourt B.H., Carvalho Mda G., Pimenta F., Nymadawa P., Altantsetseg D.,
RA   Kirsch M., Satola S.W., Cohn A., Messonnier N.E., Mayer L.W.;
RT   "Detection of bacterial pathogens in Mongolia meningitis surveillance with
RT   a new real-time PCR assay to detect Haemophilus influenzae.";
RL   Int. J. Med. Microbiol. 301:303-309(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a sn-glycero-3-phosphodiester + H2O = an alcohol + H(+) + sn-
CC         glycerol 3-phosphate; Xref=Rhea:RHEA:12969, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30879, ChEBI:CHEBI:57597,
CC         ChEBI:CHEBI:83408; EC=3.1.4.46;
CC         Evidence={ECO:0000256|ARBA:ARBA00029315};
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DR   EMBL; GQ402003; ACV30032.1; -; Genomic_DNA.
DR   AlphaFoldDB; C8CHD8; -.
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd08600; GDPD_EcGlpQ_like; 1.
DR   Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR   InterPro; IPR030395; GP_PDE_dom.
DR   InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR   PANTHER; PTHR43620:SF7; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD6; 1.
DR   PANTHER; PTHR43620; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR   Pfam; PF03009; GDPD; 1.
DR   SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR   PROSITE; PS51704; GP_PDE; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          30..344
FT                   /note="GP-PDE"
FT                   /evidence="ECO:0000259|PROSITE:PS51704"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ACV30032.1"
FT   NON_TER         344
FT                   /evidence="ECO:0000313|EMBL:ACV30032.1"
SQ   SEQUENCE   344 AA;  39533 MW;  B195545B64962BF3 CRC64;
     LGPSLLATGV LAGCSSHSSS MANTQMKSHK IIIAHRGASG YLPEHTLESK ALAFAQHADY
     LEQDLAMTKD GRLVVIHDHF LDGLTDVAKK FPHRHRKDGR YYVIDFTLKE IQSLEITENF
     ETKDGKQTQV YPNRFPLWQS HFRIHTFEDE IEFIQGLEKS TGKKVGIYPE IKAPWFHHQN
     GKDIAAETLK VLKKYGYDKK TDMVYLQTFD FNELKRIKTE LLPQMGMDLK LVQLIAYTDW
     KETQEKDSKG YWVNYNYDWM FKPGAMAKVV KYADGVGPGW YMLVNKEESK PDNIVYTPLV
     KELAQYNVEV HPYTVRKDAL PAFFTDVNQM YDALLNKSGA TGVY
//