ID C8VKC8_EMENI Unreviewed; 753 AA.
AC C8VKC8;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Metallopeptidase, putative (JCVI) {ECO:0000313|EMBL:CBF84203.1};
GN ORFNames=ANIA_10333 {ECO:0000313|EMBL:CBF84203.1};
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321 {ECO:0000313|EMBL:CBF84203.1, ECO:0000313|Proteomes:UP000000560};
RN [1] {ECO:0000313|Proteomes:UP000000560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC {ECO:0000313|Proteomes:UP000000560};
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.J., Wortman J.R., Batzoglou S.,
RA Lee S.I., Basturkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M., Hynes M., Paoletti M., Fischer R., Miller B.,
RA Dyer P., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [2] {ECO:0000313|Proteomes:UP000000560}
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC {ECO:0000313|Proteomes:UP000000560};
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the peptidase M20A family.
CC {ECO:0000256|ARBA:ARBA00006247}.
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DR EMBL; BN001306; CBF84203.1; -; Genomic_DNA.
DR RefSeq; XP_660295.1; XM_655203.1.
DR AlphaFoldDB; C8VKC8; -.
DR STRING; 227321.C8VKC8; -.
DR EnsemblFungi; CBF84203; CBF84203; ANIA_10333.
DR GeneID; 2874370; -.
DR KEGG; ani:AN2691.2; -.
DR VEuPathDB; FungiDB:AN10333; -.
DR eggNOG; KOG2275; Eukaryota.
DR HOGENOM; CLU_021802_8_4_1; -.
DR InParanoid; C8VKC8; -.
DR OMA; SDYEAHQ; -.
DR Proteomes; UP000000560; Chromosome VI.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.30.70.360; -; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR Gene3D; 3.40.630.10; Zn peptidases; 2.
DR InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR InterPro; IPR002933; Peptidase_M20.
DR InterPro; IPR011650; Peptidase_M20_dimer.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR PANTHER; PTHR42937; -; 1.
DR PANTHER; PTHR42937:SF1; DIAMINOPROPIONATE AMMONIA-LYASE; 1.
DR Pfam; PF07687; M20_dimer; 1.
DR Pfam; PF00291; PALP; 1.
DR Pfam; PF01546; Peptidase_M20; 1.
DR SUPFAM; SSF55031; Bacterial exopeptidase dimerisation domain; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000560};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 35..355
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
FT DOMAIN 547..648
FT /note="Peptidase M20 dimerisation"
FT /evidence="ECO:0000259|Pfam:PF07687"
SQ SEQUENCE 753 AA; 80160 MW; C5A9ECC43EEADD87 CRC64;
MSSRRPIFFN PLASSQRSEF PQIDGLSKFH KSLAGYSPTP LTSLPDLAAE LGVRAVLVKD
ESNRLGLPSF KVLGASWGCY RAVAAYLNLP LTVSLEEMAA RAQEKSVTLL AATKGNHGRA
VAFMARTLGI ESRIFVSETM DGPTKDRIRS EGAKVTTIKG DYDAAVLEAL KVSTEMDGAL
LIQDTALEGY EEVPSWIVEG YSSMMLEIES QLAEIGLRAT VMVTPVGVGS LANTVSTFCK
SRENPISVIV VEPDTAACLH SNLLAGKLRR IETSFTIMDG MNCGTVSTTA WSNLQRLVDA
SVTVSCYESH QAVGYLASRS IKAGPCGAAS LAALRRVKEC SESLLTEDSV VVLLSTEGPR
DYPIPLDVSS DNAVEIASTL TRINSSNPTL SLADGVGETQ ICDYLQAWFA HRGIESHRVE
PVPGRPSVVG IHRGSGGGKA LMFNGHIDTV SLASYETDAL SGAIGTRGGK QVVLGRGSLD
MKGGLASALA ALSAIKASCE PLRGDVIIAA VSDEEDASQG TRDILAAGWR ADAAVVPEPT
NEIIAHAHKG FVWVEVDILG VAAHGSNHID GVDAILHAGW FLQALEKHAS RLPIDDILGP
ATLHCGLIQG GEEASSYPAK CTITIEFRTI PGQTPQSIIS DIQRLLLEIQ SSKRNFKFAE
PRATLARPAH KIDVNHPLIE SVADCANMVT GIRPGIQSVP FWCDAALLSE AGIPSVIFGP
AGHGLHGKEE WVEVDSLLRL RGAFEKLIRD FCA
//
