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Database: UniProt
Entry: C8WMS7_EGGLE
LinkDB: C8WMS7_EGGLE
Original site: C8WMS7_EGGLE 
ID   C8WMS7_EGGLE            Unreviewed;       544 AA.
AC   C8WMS7;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   SubName: Full=Integrase catalytic region {ECO:0000313|EMBL:ACV54708.1};
GN   OrderedLocusNames=Elen_0729 {ECO:0000313|EMBL:ACV54708.1};
OS   Eggerthella lenta (strain ATCC 25559 / DSM 2243 / CCUG 17323 / JCM 9979 /
OS   KCTC 3265 / NCTC 11813 / VPI 0255 / 1899 B) (Eubacterium lentum).
OC   Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC   Eggerthella.
OX   NCBI_TaxID=479437 {ECO:0000313|EMBL:ACV54708.1, ECO:0000313|Proteomes:UP000001377};
RN   [1] {ECO:0000313|EMBL:ACV54708.1, ECO:0000313|Proteomes:UP000001377}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25559 / DSM 2243 / CCUG 17323 / JCM 9979 / KCTC 3265 /
RC   NCTC 11813 / VPI 0255 / 1899 B {ECO:0000313|Proteomes:UP000001377};
RX   PubMed=21304654; DOI=10.4056/sigs.33592;
RA   Saunders E., Pukall R., Abt B., Lapidus A., Glavina Del Rio T.,
RA   Copeland A., Tice H., Cheng J.F., Lucas S., Chen F., Nolan M., Bruce D.,
RA   Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Ovchinnikova G.,
RA   Pati A., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J.,
RA   Jeffries C.D., Chain P., Meincke L., Sims D., Brettin T., Detter J.C.,
RA   Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P., Han C.;
RT   "Complete genome sequence of Eggerthella lenta type strain (IPP VPI
RT   0255).";
RL   Stand. Genomic Sci. 1:174-182(2009).
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DR   EMBL; CP001726; ACV54708.1; -; Genomic_DNA.
DR   RefSeq; WP_009607906.1; NC_013204.1.
DR   AlphaFoldDB; C8WMS7; -.
DR   STRING; 479437.Elen_0729; -.
DR   PaxDb; 479437-Elen_0729; -.
DR   KEGG; ele:Elen_0729; -.
DR   eggNOG; COG2801; Bacteria.
DR   HOGENOM; CLU_027402_27_5_11; -.
DR   OrthoDB; 3173629at2; -.
DR   BioCyc; ELEN479437:G1GFY-735-MONOMER; -.
DR   Proteomes; UP000001377; Chromosome.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR025948; HTH-like_dom.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR048020; Transpos_IS3.
DR   NCBIfam; NF033516; transpos_IS3; 1.
DR   PANTHER; PTHR46889; TRANSPOSASE INSF FOR INSERTION SEQUENCE IS3B-RELATED; 1.
DR   PANTHER; PTHR46889:SF1; TRANSPOSASE INSO FOR INSERTION SEQUENCE ELEMENT IS911B-RELATED; 1.
DR   Pfam; PF13276; HTH_21; 1.
DR   Pfam; PF13384; HTH_23; 1.
DR   Pfam; PF00665; rve; 1.
DR   Pfam; PF13333; rve_2; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001377}.
FT   DOMAIN          379..540
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
FT   REGION          165..197
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          350..375
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   544 AA;  59440 MW;  11E2A28AE1422648 CRC64;
     MAYGKEYKEE VLSRFHASGM SMRAACSSLE GFPCAATLSA FAREEGAGLL RPPALAVPGR
     CEGRRAWEPY PLGTKREAMR LLAGGMEPRF VAGRLGIASA APVRLWASRL GRLDGLDGRS
     RPDGERERGE AVTMFARGSS VSEIAGRIGA DRRTVRRWLD KAGVERKRAT KGKGGEGVAK
     EEGGERGEWS RAWGDLPEGD PVERARLAEV RLAEALAVLD VLKAPGPGSL SNSEKRRAGE
     RARAMAARAR VDDVLRDFRI ARSTYFSQAA MAARPDRHAA LRARVRAAFE GSKGRYGSLS
     VWAALRRGEG APVRARDLAP GDMEAPVVVS EKVVRRIMRE EGLVPVQVKE RRRHSSYAGE
     TDERPANLPL REDGTHGFRA DAPGRLVVTD VTEFDLGGLK VYLSPIIDCF DGCPVAWRTS
     TRPDDELTAG SLEDALGRLE EGCAVHTDGG GNYRSARWKG VCEANGLVRS MSRKAKSPDN
     ARAEGFFGTL KQEFFYARDW KGTTKGSFVR ALDEYIVWYR DEKIKRSLGW KTIAAHRAAL
     AAAA
//
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