ID C8XKA0_NAKMY Unreviewed; 539 AA.
AC C8XKA0;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Glycoside hydrolase family 16 {ECO:0000313|EMBL:ACV78662.1};
DE Flags: Precursor;
GN OrderedLocusNames=Namu_2285 {ECO:0000313|EMBL:ACV78662.1};
OS Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / CIP 104796 / JCM
OS 9543 / NBRC 105858 / Y-104) (Microsphaera multipartita).
OC Bacteria; Actinomycetota; Actinomycetes; Nakamurellales; Nakamurellaceae;
OC Nakamurella.
OX NCBI_TaxID=479431 {ECO:0000313|EMBL:ACV78662.1, ECO:0000313|Proteomes:UP000002218};
RN [1] {ECO:0000313|Proteomes:UP000002218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700099 / DSM 44233 / CIP 104796 / JCM 9543 / NBRC 105858 /
RC Y-104 {ECO:0000313|Proteomes:UP000002218};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Ovchinnikova G., Sims D., Meincke L., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Nakamurella multipartita DSM 44233.";
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACV78662.1, ECO:0000313|Proteomes:UP000002218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700099 / DSM 44233 / CIP 104796 / JCM 9543 / NBRC 105858 /
RC Y-104 {ECO:0000313|Proteomes:UP000002218};
RX PubMed=21304699;
RA Tice H., Mayilraj S., Sims D., Lapidus A., Nolan M., Lucas S.,
RA Glavina Del Rio T., Copeland A., Cheng J.F., Meincke L., Bruce D.,
RA Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Ovchinnikova G.,
RA Pati A., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J.,
RA Jeffries C.D., Detter J.C., Brettin T., Rohde M., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.,
RA Chen F.;
RT "Complete genome sequence of Nakamurella multipartita type strain (Y-
RT 104).";
RL Stand. Genomic Sci. 2:168-175(2010).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 16 family.
CC {ECO:0000256|ARBA:ARBA00006865}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001737; ACV78662.1; -; Genomic_DNA.
DR RefSeq; WP_015747552.1; NC_013235.1.
DR AlphaFoldDB; C8XKA0; -.
DR STRING; 479431.Namu_2285; -.
DR CAZy; GH16; Glycoside Hydrolase Family 16.
DR KEGG; nml:Namu_2285; -.
DR eggNOG; COG2273; Bacteria.
DR HOGENOM; CLU_505106_0_0_11; -.
DR InParanoid; C8XKA0; -.
DR OrthoDB; 9809583at2; -.
DR Proteomes; UP000002218; Chromosome.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 1.
DR CDD; cd02182; GH16_Strep_laminarinase_like; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR000757; GH16.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR10963:SF55; GH16 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10963; GLYCOSYL HYDROLASE-RELATED; 1.
DR Pfam; PF00722; Glyco_hydro_16; 1.
DR SMART; SM00060; FN3; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS51762; GH16_2; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000313|EMBL:ACV78662.1};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000002218};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..36
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 37..539
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002994333"
FT DOMAIN 47..314
FT /note="GH16"
FT /evidence="ECO:0000259|PROSITE:PS51762"
FT DOMAIN 362..450
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 313..379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 437..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..462
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 539 AA; 55640 MW; D71C3508BDA6C187 CRC64;
MSLRFRSLTT RAAVIVTAGA LALTGAVIAT AGPAAAADPT WQTVFRDDFT GSGLPDPNKW
ILTQGTSYPG GPDAFGTGEI ETMTNRPENV DVRNGNLYIT PQRDSAGRWT SARVESAASN
YRPPAGGVMH VESRLQLPNV TGSEALGYWP AFWMLGGPYR QDRWSWPAIG EFDIMENVQG
LNWTYNVLHC GVWAGGPCNE QEGINNGVNN AGAPCKVTTC QAGMHTYGLE WDDSGPVEQL
RWYLDGELTF TVNANQVPAA TWNSLADHAG YFIILNVAMG GAFPNKLGGG PNAGTKPGVP
MVVDYVEVKY AGGSGTPTTS TPVTSTPTTS TPTTSTPTTS TPVTSTPTTS TPATPPTGGS
ASPSALRVSG STSDSLTLSW QGSAGASYEV LRSGIRIATV TGTSYTDRGL FPNTPYVYSI
RGGGVTTPEL TATLNGASAS TSTAAPTSGP TTEPTAGPTT GPVSGGPSGL KVTGTTGSTI
TLGWAGSAGA SYDVLRSGIR IATVTGTSFT DVGLFANTPY VYSIRGNGTT TPELTARIG
//
