ID C9E551_VIBCL Unreviewed; 413 AA.
AC C9E551;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Integrase {ECO:0000313|EMBL:ACV96374.1};
GN ORFNames=ICEVCHIND5_0003 {ECO:0000313|EMBL:ACV96374.1};
OS Vibrio cholerae Ind5.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=663914 {ECO:0000313|EMBL:ACV96374.1};
RN [1] {ECO:0000313|EMBL:ACV96374.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Ind5 {ECO:0000313|EMBL:ACV96374.1};
RX PubMed=20041216; DOI=10.1371/journal.pgen.1000786;
RA Wozniak R.A., Fouts D.E., Spagnoletti M., Colombo M.M., Ceccarelli D.,
RA Garriss G., Dery C., Burrus V., Waldor M.K.;
RT "Comparative ICE genomics: insights into the evolution of the SXT/R391
RT family of ICEs.";
RL PLoS Genet. 5:E1000786-E1000786(2009).
RN [2] {ECO:0000313|EMBL:ACV96374.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Ind5 {ECO:0000313|EMBL:ACV96374.1};
RA Fouts D., Durkin S., Wozniak R., Waldor M.;
RT "Vibrio cholerae ICEVchInd5.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GQ463142; ACV96374.1; -; Genomic_DNA.
DR AlphaFoldDB; C9E551; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 3.30.160.390; Integrase, DNA-binding domain; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR038488; Integrase_DNA-bd_sf.
DR InterPro; IPR025166; Integrase_DNA_bind_dom.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004107; Integrase_SAM-like_N.
DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR Pfam; PF13356; Arm-DNA-bind_3; 1.
DR Pfam; PF14659; Phage_int_SAM_3; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248};
KW Viral genome integration {ECO:0000256|ARBA:ARBA00023195};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 98..179
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 203..390
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
SQ SEQUENCE 413 AA; 48092 MW; 6A88D411127B50DB CRC64;
MALSVSWLDA RLNKEAKETV VKADRDGLSA RVSPKGKIVF QFRYRFDGKQ QRVDIGTYPL
MKLAEARNEL DRLRAVLDQG RNPKLYLQQE RAKYSANQSF ESIFRDWIDS AGKQGLKEKT
WHYQKRSSEI YLLPRLGKYP LTDITELSLR NCLREVSESS PSNTERLVSV LHKFYDWLID
EQILEINAAA GITAKKVGGK KGKRTRVLND NEIRILWRYL HESKITEKNR IYIKLLLLLG
GRKGELIQAE KHHFDLQSAM WTVPIEIRKQ GEKIGAPIMR PLIKPAIELI ELAMQMSKST
YLFPANGQEE LATNGFDTTI PNNVKIWARR SLGIEMEHWS MHDLRRTMRT RMSAITTQEV
AELMIGHSKK GLDAIYNQYQ YLDEMRHAYD VWYQQLETII EPTGFPFNWR FGQ
//
