ID C9J012_HUMAN Unreviewed; 77 AA.
AC C9J012;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Rhophilin associated tail protein 1 {ECO:0000313|Ensembl:ENSP00000418931.1};
DE Flags: Fragment;
GN Name=ROPN1 {ECO:0000313|Ensembl:ENSP00000418931.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000418931.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000418931.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16641997; DOI=10.1038/nature04728;
RA Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O.,
RA Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X.,
RA Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT "The DNA sequence, annotation and analysis of human chromosome 3.";
RL Nature 440:1194-1198(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000418931.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC {ECO:0000256|ARBA:ARBA00004230}.
CC -!- SIMILARITY: Belongs to the ropporin family.
CC {ECO:0000256|ARBA:ARBA00035651}.
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DR EMBL; AC117381; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; C9J012; -.
DR SMR; C9J012; -.
DR MassIVE; C9J012; -.
DR PeptideAtlas; C9J012; -.
DR ProteomicsDB; 7876; -.
DR Antibodypedia; 32969; 61 antibodies from 15 providers.
DR Ensembl; ENST00000496145.5; ENSP00000418931.1; ENSG00000065371.18.
DR UCSC; uc062nei.1; human.
DR HGNC; HGNC:17692; ROPN1.
DR VEuPathDB; HostDB:ENSG00000065371; -.
DR GeneTree; ENSGT00390000012731; -.
DR HOGENOM; CLU_069829_2_1_1; -.
DR OMA; TNKQICI; -.
DR Proteomes; UP000005640; Chromosome 3.
DR Bgee; ENSG00000065371; Expressed in sperm and 84 other cell types or tissues.
DR ExpressionAtlas; C9J012; baseline and differential.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR CDD; cd23019; DD_ROP; 1.
DR Gene3D; 1.20.890.10; cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain; 1.
DR InterPro; IPR047844; ROP_DD.
DR PANTHER; PTHR14952; ROPPORIN-1-LIKE PROTEIN; 1.
DR PANTHER; PTHR14952:SF18; ROPPORIN-1A; 1.
DR SUPFAM; SSF47391; Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit; 1.
PE 1: Evidence at protein level;
KW Cell projection {ECO:0000256|ARBA:ARBA00023069};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW Proteomics identification {ECO:0007829|PeptideAtlas:C9J012,
KW ECO:0007829|ProteomicsDB:C9J012};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT NON_TER 77
FT /evidence="ECO:0000313|Ensembl:ENSP00000418931.1"
SQ SEQUENCE 77 AA; 8758 MW; 2CF24759BF4418C6 CRC64;
MAQTDKPTCI PPELPKMLKE FAKAAIRVQP QDLIQWAADY FEALSRGETP PVRERSERVA
LCNRAELTPE LLKILHS
//
