ID C9J885_HUMAN Unreviewed; 126 AA.
AC C9J885;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Integrator complex subunit 6 {ECO:0000313|Ensembl:ENSP00000417707.1};
DE Flags: Fragment;
GN Name=INTS6 {ECO:0000313|Ensembl:ENSP00000417707.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000417707.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000417707.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057823; DOI=10.1038/nature02379;
RA Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L.,
RA Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S.,
RA Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P.,
RA Ambrose K.D., Andrews D.T., Ashwell R.I.S., Babbage A.K., Bagguley C.L.,
RA Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P.,
RA Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P.,
RA Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C.,
RA Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P.,
RA Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L.,
RA Frankish A.G., Frankland J., French L., Garner P., Garnett J.,
RA Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M.,
RA Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D.,
RA Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D.,
RA Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S.,
RA Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J.,
RA Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S.,
RA Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S.,
RA Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R.,
RA Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W.,
RA Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P.,
RA Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L.,
RA Coulson A., Durbin R., Hubbard T., Sulston J.E., Beck S., Bentley D.R.,
RA Rogers J., Ross M.T.;
RT "The DNA sequence and analysis of human chromosome 13.";
RL Nature 428:522-528(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000417707.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AL137780; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL354820; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; C9J885; -.
DR SMR; C9J885; -.
DR MassIVE; C9J885; -.
DR MaxQB; C9J885; -.
DR PeptideAtlas; C9J885; -.
DR ProteomicsDB; 9007; -.
DR Antibodypedia; 730; 179 antibodies from 26 providers.
DR Ensembl; ENST00000483288.5; ENSP00000417707.1; ENSG00000102786.15.
DR UCSC; uc058xea.1; human.
DR HGNC; HGNC:14879; INTS6.
DR VEuPathDB; HostDB:ENSG00000102786; -.
DR GeneTree; ENSGT00390000016655; -.
DR OMA; DFTLPMH; -.
DR ChiTaRS; INTS6; human.
DR Proteomes; UP000005640; Chromosome 13.
DR Bgee; ENSG00000102786; Expressed in secondary oocyte and 186 other cell types or tissues.
DR ExpressionAtlas; C9J885; baseline and differential.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR12957; DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED; 1.
DR PANTHER; PTHR12957:SF23; INTEGRATOR COMPLEX SUBUNIT 6; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:C9J885,
KW ECO:0007829|MaxQB:C9J885};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 6..118
FT /note="VWFA"
FT /evidence="ECO:0000259|Pfam:PF13519"
FT NON_TER 126
FT /evidence="ECO:0000313|Ensembl:ENSP00000417707.1"
SQ SEQUENCE 126 AA; 14027 MW; E5931140C5B021B4 CRC64;
MNQRSHLGTT YLDTAKGAVE TFMKLRARDP ASRGDRYMLV TFEEPPYAIK AGWKENHATF
MNELKNLQAE GLTTLGQSLR TAFDLLNLNR LVTGIDNYGQ GRNPFFLEPA IIITITDGSK
LTTTSG
//
