ID C9KJ71_9FIRM Unreviewed; 556 AA.
AC C9KJ71;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE SubName: Full=Glycosyl hydrolase, family 43 {ECO:0000313|EMBL:EEX69937.1};
GN ORFNames=MITSMUL_03068 {ECO:0000313|EMBL:EEX69937.1};
OS Mitsuokella multacida DSM 20544.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Selenomonadaceae;
OC Mitsuokella.
OX NCBI_TaxID=500635 {ECO:0000313|EMBL:EEX69937.1, ECO:0000313|Proteomes:UP000003671};
RN [1] {ECO:0000313|EMBL:EEX69937.1, ECO:0000313|Proteomes:UP000003671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20544 {ECO:0000313|EMBL:EEX69937.1,
RC ECO:0000313|Proteomes:UP000003671};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEX69937.1}.
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DR EMBL; ABWK02000001; EEX69937.1; -; Genomic_DNA.
DR RefSeq; WP_005838896.1; NZ_GG697141.2.
DR AlphaFoldDB; C9KJ71; -.
DR STRING; 500635.MITSMUL_03068; -.
DR CAZy; GH43; Glycoside Hydrolase Family 43.
DR GeneID; 78516798; -.
DR PATRIC; fig|500635.8.peg.64; -.
DR eggNOG; COG3507; Bacteria.
DR HOGENOM; CLU_016508_2_1_9; -.
DR Proteomes; UP000003671; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR041542; GH43_C2.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR42812; BETA-XYLOSIDASE; 1.
DR PANTHER; PTHR42812:SF12; BETA-XYLOSIDASE-RELATED; 1.
DR Pfam; PF17851; GH43_C2; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187}.
FT DOMAIN 347..549
FT /note="Beta-xylosidase C-terminal Concanavalin A-like"
FT /evidence="ECO:0000259|Pfam:PF17851"
FT REGION 324..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 15
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 188
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 129
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 556 AA; 62162 MW; BB286F3FE0016F06 CRC64;
MGIICNPIIS GMAPDPSILR VGDDYYLATS TFHWLPGIPI YHSRNLADWE LLTHVLKGTE
VNLRGTHTPA GIWAPHLSYD AQAKKYWLVF CHMKNMAGRE FNAESYAMSA DDITGPWSDP
VYLTSIGFDP SLYHEDGHHY LAILEWETRS GYQAPGTIVM AEVDLRTGKL VDGWHRITNG
FTTRGCVEAP QIYKHGAYYY MLAASGGTGY AHGVEMGRAE KIFGPYEPNP TGEPILTSSP
RHLFSLGDPD AGHFEMYNPK SLMQKAGHGS LVETPEHEWY IAHLMARPLP GTKLNPLGRE
TALQKMHWTE DGWLELADGS NVAKMTTEAP CSQPSEPRDA QEDDVYDAFS SGVLSKKFMA
PYHQPDLSWV SVQHGHLVLC GRESFFSQND PSILATRATS FSYQLQTKLD FHPVHYSQTA
GGGLYYDSNN WIYAYVGLSD KEDQRVISIL QAKLGQRIAF DFDTVRIPDG AVPELRWQYH
YGKAQAFYRL DEGAEWQAIA DACDVSYLSD EGVNGEPGEI GGFTALFNFI GSVDAYQHDS
QAEFFYYQVK SDQANQ
//
