ID C9P0M4_VIBME Unreviewed; 595 AA.
AC C9P0M4;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Xaa-Pro aminopeptidase {ECO:0000313|EMBL:EEX38557.1};
DE EC=3.4.11.9 {ECO:0000313|EMBL:EEX38557.1};
GN ORFNames=VIB_000021 {ECO:0000313|EMBL:EEX38557.1};
OS Vibrio metschnikovii CIP 69.14.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=675813 {ECO:0000313|EMBL:EEX38557.1, ECO:0000313|Proteomes:UP000005604};
RN [1] {ECO:0000313|EMBL:EEX38557.1, ECO:0000313|Proteomes:UP000005604}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIP 69.14 {ECO:0000313|EMBL:EEX38557.1,
RC ECO:0000313|Proteomes:UP000005604};
RG Los Alamos National Laboratory (LANL);
RG National Microbial Pathogen Data Resource (NMPDR);
RA Munk A.C., Tapia R., Green L., Rogers Y., Detter J.C., Bruce D.,
RA Brettin T.S., Colwell R.R., Huq A., Grim C.J., Hasan N.A., Bartels D.,
RA Vonstein V.;
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
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DR EMBL; ACZO01000002; EEX38557.1; -; Genomic_DNA.
DR RefSeq; WP_004393849.1; NZ_ACZO01000002.1.
DR AlphaFoldDB; C9P0M4; -.
DR STRING; 675813.VIB_000021; -.
DR GeneID; 79889035; -.
DR eggNOG; COG0006; Bacteria.
DR Proteomes; UP000005604; Unassembled WGS sequence.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:EEX38557.1};
KW Hydrolase {ECO:0000313|EMBL:EEX38557.1};
KW Protease {ECO:0000313|EMBL:EEX38557.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005604}.
FT DOMAIN 8..139
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 309..524
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 534..593
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 595 AA; 66221 MW; E74E934F6B505636 CRC64;
MSHPIAQRIT ELRHWLIQQG LDALIVPHED EYLGEYVPIQ NERLEWVTGF TGSAGAAVIT
SDNAAIFADG RYTVQVPKQV PSDIFQYRHL IEEPYLQWIT EQLPKGSKIG YDPRMHRASW
LTNAQQLFAG EYSLVAITEN PIDLLWQDRP APVTSAMRLM PVEQVGVDCH TKRATIANLL
QAKKADCAIL TELDSICWLL NIRGLDVARL PVLLSHAIIH ADASVDFFFE PSRLATGFEQ
HVGAGVRVYH PEQLQSRLEQ LTGRTVMLDP ATSNAWFTLV LQNAGAKLIN DSDPCLLPKA
AKNPTEVAGM KACHIRDGVA MSKFLSWLDH EVAAGRLYNE AQLADQLYAF RAQDPTLADL
SFDTISAAGS NAAMCHYNHL NQPQPGELSL NSLYLVDSGG QYLDGTTDIT RTIAIGQPSA
EMKHQFTLVL KGHIALAQAR FPAGTCGHQL DALARQYLWA EGYDYDHGTG HGVGHFLSVH
EGPQRISKVH NPVALRPGMV LSNEPGYYRA DEFGIRIENL ELVVEIPTQG DKNMLGFEAL
TRCPIDTRVI DFSLLAAYEI AWLNDYHQKV WRDISPLVES EVKLWLEKAT QPITL
//
