ID C9RMH3_FIBSS Unreviewed; 556 AA.
AC C9RMH3;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Glycoside hydrolase, family 43 {ECO:0000313|EMBL:ADL24798.1};
GN OrderedLocusNames=FSU_3190 {ECO:0000313|EMBL:ADL24798.1};
OS Fibrobacter succinogenes (strain ATCC 19169 / S85).
OC Bacteria; Fibrobacterota; Fibrobacteria; Fibrobacterales; Fibrobacteraceae;
OC Fibrobacter.
OX NCBI_TaxID=59374 {ECO:0000313|EMBL:ADL24798.1, ECO:0000313|Proteomes:UP000000517};
RN [1] {ECO:0000313|Proteomes:UP000000517}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19169 / S85 {ECO:0000313|Proteomes:UP000000517};
RA Durkin A.S., Nelson K.E., Morrison M., Forsberg C.W., Wilson D.B.,
RA Russell J.B., Cann I.K.O., Mackie R.I., White B.A.;
RT "Complete sequence of Fibrobacter succinogenes subsp. succinogenes S85.";
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
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DR EMBL; CP002158; ADL24798.1; -; Genomic_DNA.
DR RefSeq; WP_014547223.1; NC_017448.1.
DR AlphaFoldDB; C9RMH3; -.
DR STRING; 59374.FSU_3190; -.
DR CAZy; GH43; Glycoside Hydrolase Family 43.
DR GeneID; 34756965; -.
DR KEGG; fsc:FSU_3190; -.
DR PATRIC; fig|59374.8.peg.3051; -.
DR eggNOG; COG3507; Bacteria.
DR HOGENOM; CLU_516542_0_0_0; -.
DR OrthoDB; 9763933at2; -.
DR Proteomes; UP000000517; Chromosome.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd18618; GH43_Xsa43E-like; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR PANTHER; PTHR43772:SF2; BETA-1,4-XYLOSIDASE (EUROFUNG); 1.
DR PANTHER; PTHR43772; ENDO-1,4-BETA-XYLANASE; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00022651};
KW Signal {ECO:0000256|SAM:SignalP};
KW Xylan degradation {ECO:0000256|ARBA:ARBA00022651}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..556
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003000238"
FT ACT_SITE 45
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 222
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 176
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 556 AA; 62221 MW; D7921FF088075095 CRC64;
MRTRGSGFFT TLEWAFFGLF CLFGAFGAQS AFAANPLTTD FYSADAAALV HNDSLFIFAG
HDEQGPQGNN NKAFIMNDWH VLVTDDMEHY HDYGAVLSVK TFKWANASAF AGHCEYRNGK
FYWYVAVHHG TIKENGSEGF AIGVAVADHP SGPWKDAIGQ ALITDNTPND VKLNIDPAIF
YDGDDIWMYW GSWSAGRRVK LKENMIELAS TPEDIKIKDF FEAPWMHYFR GNYYFSYASG
YPSTTNYSMA PSLNGPWTQK GVINDKMDNS ETNHQAIFKY LGHWYFMYHG ANSPGGWTYR
RSVNIDYLYY DRDGLIQKIK HTDGVDPVNN ALLEEGGYRL TVSHSNLALE DNDGIVVQQT
ADEKNEAQLW VLAHGDSARY YTLKNFATGR YYCPPKTLLD TVKTSETSCE IRIENASAKK
GYFLFADYDS DYLGDVLNIS KEVGMPVITW VRTGTDNQKV QFAKAELPKV EPPTDSGNGG
TTGIARGILN APALQQVHYD ASARVIRLGA EASWALLDVN GVVVRRGYGR EIQVRSVRSG
MYFVRAARTT AKVLVK
//
